caa a22 4500 469116005 CHVBK 20180323133124.0 cr unu---uuuuu 170328e19921201xx s 000 0 eng 10.1007/BF02755880 doi (NATIONALLICENCE)springer-10.1007/BF02755880 Distribution of gold in human platelets after in-vitro interaction and during chrysotherapy with gold sodium thiomalate [Elektronische Daten] [Y. Kassam, W. Kean, C. Lock, G. Simon, W. Buchanan] We have studied the distribution of gold in platelets from patients with rheumatoid arthritis (RA) undergoing chrysotherapy and, in vitro, in platelets reacted with gold sodium thiomalate. In vitro, electron dense fibrillar particles within membrane bound structures were detected in preparations containing 50 μg/ml or more of Au. Energy dispersive spectroscopy confirmed the presence of gold and sulphur in these particles. Gold was detected in platelets from RA patients by neutron activation analysis, but not by electron microscopy. Kluwer Acedemic Publishers, 1992 chrysotherapy nationallicence electron microscopy nationallicence energy dispersive spectroscopy nationallicence neutron activation analysis nationallicence Kassam Y. Department of Medicine (Rheumatology), McMaster University and Chedoke-McMaster Hospitals, L8S 4M1, Hamilton, Ontario, Canada aut Kean W. Department of Medicine (Rheumatology), McMaster University and Chedoke-McMaster Hospitals, L8S 4M1, Hamilton, Ontario, Canada aut Lock C. Department of Pathology, McMaster University and Chedoke-McMaster Hospitals, L8S 4M1, Hamilton, Ontario, Canada aut Simon G. Department of Pathology, McMaster University and Chedoke-McMaster Hospitals, L8S 4M1, Hamilton, Ontario, Canada aut Buchanan W. Department of Medicine (Rheumatology), McMaster University and Chedoke-McMaster Hospitals, L8S 4M1, Hamilton, Ontario, Canada aut InflammoPharmacology Birkhäuser-Verlag 1/4(1992-12-01), 295-303 0925-4692 1:4<295 1992 1 10787 https://doi.org/10.1007/BF02755880 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02755880 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kassam Y. Department of Medicine (Rheumatology), McMaster University and Chedoke-McMaster Hospitals, L8S 4M1, Hamilton, Ontario, Canada aut NATIONALLICENCE 700 1- Kean W. Department of Medicine (Rheumatology), McMaster University and Chedoke-McMaster Hospitals, L8S 4M1, Hamilton, Ontario, Canada aut NATIONALLICENCE 700 1- Lock C. Department of Pathology, McMaster University and Chedoke-McMaster Hospitals, L8S 4M1, Hamilton, Ontario, Canada aut NATIONALLICENCE 700 1- Simon G. Department of Pathology, McMaster University and Chedoke-McMaster Hospitals, L8S 4M1, Hamilton, Ontario, Canada aut NATIONALLICENCE 700 1- Buchanan W. Department of Medicine (Rheumatology), McMaster University and Chedoke-McMaster Hospitals, L8S 4M1, Hamilton, Ontario, Canada aut NATIONALLICENCE 773 0- InflammoPharmacology Birkhäuser-Verlag 1/4(1992-12-01), 295-303 0925-4692 1:4<295 1992 1 10787 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer