caa a22 4500 469116730 CHVBK 20180323133126.0 cr unu---uuuuu 170328e19920601xx s 000 0 eng 10.1007/BF00172768 doi (NATIONALLICENCE)springer-10.1007/BF00172768 Quality of life in patients with intracranial tumors on the basis of Karnofsky's performance status [Elektronische Daten] [W. Sachsenheimer, W. Piotrowski, T. Bimmler] Summary: This prospective clinical trial (1983-1989) compares life-quality scores according to Karnofsky in patients with intra-cranial who had been operated upon. Karnofsky's performance status was evaluated during a follow-up period of 36 months. The patients were between 20 to 77 years of age; 132 patients had an astrocytoma grade III or IV; 42 patients with brain metastases were investigated; 72 had an astrocytoma grade I + II, and 144 had a meningioma. The median survival in patients with astrocytomas grade III or IV was 12 months; a short period with nearly normal activity (Karnofsky score 75) was followed by rapid deterioration. In patients with brain metastases, postoperatively the median functional ability reached its highest value three weeks after treatment and then decreased continuously (average score from 50-25). In patients with astrocytomas grade I and II, life-quality was reasonably good (mean score up to 75). The score was observed to increase slightly during the first year after treatment. A performance status improvement up to 80 could be obtained in patients with meningiomas; however, 35% were left unfit for work. Kluwer Academic Publishers, 1992 intracranial tumors nationallicence quality of life nationallicence Karnofsky rating nationallicence Sachsenheimer W. Fakultät für klinische Medizin Mannheim der Universität Heidelberg, Neurologische Klinik, Theodor Kutzer Ufer, D-6800, Mannheim, Germany aut Piotrowski W. Fakultät für klinische Medizin Mannheim der Universität Heidelberg, Neurologische Klinik, Theodor Kutzer Ufer, D-6800, Mannheim, Germany aut Bimmler T. Fakultät für klinische Medizin Mannheim der Universität Heidelberg, Neurologische Klinik, Theodor Kutzer Ufer, D-6800, Mannheim, Germany aut Journal of Neuro-Oncology Kluwer Academic Publishers 13/2(1992-06-01), 177-181 0167-594X 13:2<177 1992 13 11060 https://doi.org/10.1007/BF00172768 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00172768 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sachsenheimer W. Fakultät für klinische Medizin Mannheim der Universität Heidelberg, Neurologische Klinik, Theodor Kutzer Ufer, D-6800, Mannheim, Germany aut NATIONALLICENCE 700 1- Piotrowski W. Fakultät für klinische Medizin Mannheim der Universität Heidelberg, Neurologische Klinik, Theodor Kutzer Ufer, D-6800, Mannheim, Germany aut NATIONALLICENCE 700 1- Bimmler T. Fakultät für klinische Medizin Mannheim der Universität Heidelberg, Neurologische Klinik, Theodor Kutzer Ufer, D-6800, Mannheim, Germany aut NATIONALLICENCE 773 0- Journal of Neuro-Oncology Kluwer Academic Publishers 13/2(1992-06-01), 177-181 0167-594X 13:2<177 1992 13 11060 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer