caa a22 4500 469116986 CHVBK 20180323133127.0 cr unu---uuuuu 170328e19921101xx s 000 0 eng 10.1007/BF00172602 doi (NATIONALLICENCE)springer-10.1007/BF00172602 The prognostic significance of postoperative residual contrast enhancement on CT scan in pediatric patients with medulloblastoma [Elektronische Daten] [Jeffrey Bourne, Russell Geyer, Mitchel Berger, Brian Griffin, Jerrold Milstein] The clinical and therapeutic features of 20 patients with medulloblastoma treated at Childrens' Hospital and Medical Center, Seattle, from 1980 to 1987, were retrospectively analyzed with regard to prognosis. The overall actuarial 5-year survival rate was 63%, with 57% of patients free from recurrence at 5 years. Residual contrast enhancement on CT scans taken immediately postoperatively was associated with a significantly decreased 5-year recurrence-free survival rate; the 5-year recurrence-free survival rate was 100% for those patients without post-operative residual enhancement compared to 41% for those patients with residual enhancement. A high risk group of patients with residual contrast enhancement persisting one year following diagnosis was identified. No patient in this group survived without disease progression. Other factors, including sex, age at diagnosis, evidence of tumor dissemination, or extent of surgical resection as reported by the neurosurgeon, did not significantly influence prognosis. Kluwer Academic Publishers, 1992 medulloblastoma nationallicence pediatric brain tumor nationallicence computerized tomography nationallicence Bourne Jeffrey PediatricsChildren's Hospital & Med Center, University of Washington, Seattle, Washington, USA aut Geyer Russell PediatricsChildren's Hospital & Med Center, University of Washington, Seattle, Washington, USA aut Berger Mitchel Neurological Surgery, Children's Hospital & Med Center, University of Washington, Seattle, Washington, USA aut Griffin Brian Radiation Oncology, Children's Hospital & Med Center, University of Washington, Seattle, Washington, USA aut Milstein Jerrold Neurology, Children's Hospital & Med Center, University of Washington, Seattle, Washington, USA aut Journal of Neuro-Oncology Kluwer Academic Publishers 14/3(1992-11-01), 263-270 0167-594X 14:3<263 1992 14 11060 https://doi.org/10.1007/BF00172602 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00172602 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bourne Jeffrey PediatricsChildren's Hospital & Med Center, University of Washington, Seattle, Washington, USA aut NATIONALLICENCE 700 1- Geyer Russell PediatricsChildren's Hospital & Med Center, University of Washington, Seattle, Washington, USA aut NATIONALLICENCE 700 1- Berger Mitchel Neurological Surgery, Children's Hospital & Med Center, University of Washington, Seattle, Washington, USA aut NATIONALLICENCE 700 1- Griffin Brian Radiation Oncology, Children's Hospital & Med Center, University of Washington, Seattle, Washington, USA aut NATIONALLICENCE 700 1- Milstein Jerrold Neurology, Children's Hospital & Med Center, University of Washington, Seattle, Washington, USA aut NATIONALLICENCE 773 0- Journal of Neuro-Oncology Kluwer Academic Publishers 14/3(1992-11-01), 263-270 0167-594X 14:3<263 1992 14 11060 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer