caa a22 4500 469118482 CHVBK 20180323133131.0 cr unu---uuuuu 170328e19921101xx s 000 0 eng 10.1007/BF02245887 doi (NATIONALLICENCE)springer-10.1007/BF02245887 Hypouricemic effect of zuclopenthixol: a potential marker of drug compliance? [Elektronische Daten] [Meir Bloch, Eitan Gur, Arieh Shalev] Twelve newly-admitted psychotic patients were treated with clinical doses of zuclopenthixol (ZPT). Plasma uric acid (PUA) was measured before and during treatment. ZPT reduced PUA in all the patients by an average of 29.6% (P<0.001). PUA levels during treatment correlated with those obtained before treatment (R=0.871,P<0.0002). PUA returned to initial levels on discontinuation of treatment. Uric acid excretion increased during treatment. It is concluded that ZPT is a potent uricosuric agent, capable of producing persistent hypouricemia while administered. Such hypouricemia might be a useful indicator of drug compliance. Springer-Verlag, 1992 Zuclopenthixol nationallicence Neuroleptics nationallicence Side-effects nationallicence Uric acid nationallicence Uricosuric agents nationallicence Non-compliance nationallicence Bloch Meir Department of Psychiatry, Hadassah University Hospital, P.O. Box 12000, 91120, Jerusalem, Israel aut Gur Eitan Department of Psychiatry, Hadassah University Hospital, P.O. Box 12000, 91120, Jerusalem, Israel aut Shalev Arieh Department of Psychiatry, Hadassah University Hospital, P.O. Box 12000, 91120, Jerusalem, Israel aut Psychopharmacology Springer-Verlag 109/3(1992-11-01), 377-378 0033-3158 109:3<377 1992 109 213 https://doi.org/10.1007/BF02245887 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02245887 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bloch Meir Department of Psychiatry, Hadassah University Hospital, P.O. Box 12000, 91120, Jerusalem, Israel aut NATIONALLICENCE 700 1- Gur Eitan Department of Psychiatry, Hadassah University Hospital, P.O. Box 12000, 91120, Jerusalem, Israel aut NATIONALLICENCE 700 1- Shalev Arieh Department of Psychiatry, Hadassah University Hospital, P.O. Box 12000, 91120, Jerusalem, Israel aut NATIONALLICENCE 773 0- Psychopharmacology Springer-Verlag 109/3(1992-11-01), 377-378 0033-3158 109:3<377 1992 109 213 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer