caa a22 4500 469119586 CHVBK 20180323133134.0 cr unu---uuuuu 170328e19920901xx s 000 0 eng 10.1007/BF02247428 doi (NATIONALLICENCE)springer-10.1007/BF02247428 Use of phenylpropanolamine to reduce nicotine cessation induced weight gain in rats [Elektronische Daten] [Suzan Winders, Thane Dykstra, Mace Coday, John Amos, Mary Wilson, David Wilkins] The present study was conducted to determine if phenylpropanolamine (PPA) administered during the first week of nicotine termination could reduce or eliminate the body weight rebound which accompanies nicotine cessation. Sprague-Dawley rats were administered nicotine for 2 weeks after which they received either PPA or saline for 1 week. Control animals received saline during both drug periods. Body weight, food consumption, and water consumption were measured daily before drug, during nicotine and PPA administration, and for 14 days after PPA administration. In contrast to animals receiving saline upon termination of nicotine, animals receiving PPA did not gain weight at an accelerated rate. Termination of PPA did not result in a body weight rebound. To the extent that these results generalize to humans, they suggest that PPA could be used to reduce or eliminate postcessation weight gain in smokers who stop smoking. Springer-Verlag, 1992 Nicotine nationallicence Phenylpropanolamine nationallicence Body weight nationallicence Food consumption nationallicence Water consumption nationallicence Winders Suzan Department of Psychology, Memphis State University, 38152, Memphis, TN, USA aut Dykstra Thane Department of Psychology, University of Nevada, Reno, NV, USA aut Coday Mace Department of Psychology, Memphis State University, 38152, Memphis, TN, USA aut Amos John Department of Psychology, Memphis State University, 38152, Memphis, TN, USA aut Wilson Mary Department of Psychology, Memphis State University, 38152, Memphis, TN, USA aut Wilkins David Department of Psychology, Memphis State University, 38152, Memphis, TN, USA aut Psychopharmacology Springer-Verlag 108/4(1992-09-01), 501-506 0033-3158 108:4<501 1992 108 213 https://doi.org/10.1007/BF02247428 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02247428 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Winders Suzan Department of Psychology, Memphis State University, 38152, Memphis, TN, USA aut NATIONALLICENCE 700 1- Dykstra Thane Department of Psychology, University of Nevada, Reno, NV, USA aut NATIONALLICENCE 700 1- Coday Mace Department of Psychology, Memphis State University, 38152, Memphis, TN, USA aut NATIONALLICENCE 700 1- Amos John Department of Psychology, Memphis State University, 38152, Memphis, TN, USA aut NATIONALLICENCE 700 1- Wilson Mary Department of Psychology, Memphis State University, 38152, Memphis, TN, USA aut NATIONALLICENCE 700 1- Wilkins David Department of Psychology, Memphis State University, 38152, Memphis, TN, USA aut NATIONALLICENCE 773 0- Psychopharmacology Springer-Verlag 108/4(1992-09-01), 501-506 0033-3158 108:4<501 1992 108 213 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer