caa a22 4500 469119616 CHVBK 20180323133134.0 cr unu---uuuuu 170328e19920901xx s 000 0 eng 10.1007/BF02247416 doi (NATIONALLICENCE)springer-10.1007/BF02247416 Psychomotor performance in smokers following single and repeated doses of nicotine gum [Elektronische Daten] [N. Sherwood, J. Kerr, I. Hindmarch] The psychomotor effects of single and repeated doses of 2 mg nicotine gum were investigated in 13 regular smokers who had abstained from tobacco overnight. In comparison to baseline, a first dose of nicotine led to significantly raised critical flicker fusion thresholds, faster motor reaction times, improved compensatory tracking performance, and faster short-term memory reaction times. Performance after a second and third dose of nicotine remained significantly improved on all measures in comparison to baseline, and absolutely improved when comparing first and third nicotine doses on measures of sensorimotor performance. Throughout, comparisons with a placebo gum condition confirmed that these effects were genuine and not subject to the development of acute nicotine tolerance, suggesting that the enhancement of psychomotor performance experienced by smokers after a first cigarette may be maintained by repeated smoking. Springer-Verlag, 1992 Nicotine gum nationallicence Psychomotor performance nationallicence Smoking nationallicence Sherwood N. Human Psychopharmacology Research Unit, Robens Institute, University of Surrey, Milford Hospital, GU7 1UF, Godalming, UK aut Kerr J. Human Psychopharmacology Research Unit, Robens Institute, University of Surrey, Milford Hospital, GU7 1UF, Godalming, UK aut Hindmarch I. Human Psychopharmacology Research Unit, Robens Institute, University of Surrey, Milford Hospital, GU7 1UF, Godalming, UK aut Psychopharmacology Springer-Verlag 108/4(1992-09-01), 432-436 0033-3158 108:4<432 1992 108 213 https://doi.org/10.1007/BF02247416 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02247416 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sherwood N. Human Psychopharmacology Research Unit, Robens Institute, University of Surrey, Milford Hospital, GU7 1UF, Godalming, UK aut NATIONALLICENCE 700 1- Kerr J. Human Psychopharmacology Research Unit, Robens Institute, University of Surrey, Milford Hospital, GU7 1UF, Godalming, UK aut NATIONALLICENCE 700 1- Hindmarch I. Human Psychopharmacology Research Unit, Robens Institute, University of Surrey, Milford Hospital, GU7 1UF, Godalming, UK aut NATIONALLICENCE 773 0- Psychopharmacology Springer-Verlag 108/4(1992-09-01), 432-436 0033-3158 108:4<432 1992 108 213 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer