caa a22 4500 46912041X CHVBK 20180323133137.0 cr unu---uuuuu 170328e19920601xx s 000 0 eng 10.1007/BF02245156 doi (NATIONALLICENCE)springer-10.1007/BF02245156 Effects of fenfluramine and para-chloroamphetamine on sexual behavior of male rats [Elektronische Daten] [Mark Foreman, James Hall, Ronald Love] The present studies have evaluated the effects of pharmacologically induced release serotonin on sexual responses of male rats during exposure to a sexually receptive female rat. Following acute administration of fenfluramine or para-chloroamphetamine (PCA), significant dose-related decreases in copulatory rate and copulatory efficiency, and increases in ejaculatory latency were observed. These effects were not observed when the animals were pretreated with LY53857, a 5-HT1c/2 antagonist. These studies indicate that acute release of serotonin evoked by these releasing agents has inhibitory effects on sexual sexual drive, capacity to achieve erection and threshold for ejaculation, and these effects are mediated by either the 5-HT1c or 5-HT2 receptor. Springer-Verlag, 1992 Sexual behavior nationallicence Serotonin nationallicence Fenfluramine nationallicence Para-chloroamphetamine nationallicence LY53857 nationallicence 5-HT1c receptor and 5-HT2 receptor nationallicence Foreman Mark Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, 46285, Indianapolis, IN, USA aut Hall James Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, 46285, Indianapolis, IN, USA aut Love Ronald Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, 46285, Indianapolis, IN, USA aut Psychopharmacology Springer-Verlag 107/2-3(1992-06-01), 327-330 0033-3158 107:2-3<327 1992 107 213 https://doi.org/10.1007/BF02245156 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02245156 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Foreman Mark Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, 46285, Indianapolis, IN, USA aut NATIONALLICENCE 700 1- Hall James Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, 46285, Indianapolis, IN, USA aut NATIONALLICENCE 700 1- Love Ronald Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, 46285, Indianapolis, IN, USA aut NATIONALLICENCE 773 0- Psychopharmacology Springer-Verlag 107/2-3(1992-06-01), 327-330 0033-3158 107:2-3<327 1992 107 213 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer