caa a22 4500 469121319 CHVBK 20180323133139.0 cr unu---uuuuu 170328e19920301xx s 000 0 eng 10.1007/BF02245423 doi (NATIONALLICENCE)springer-10.1007/BF02245423 A dose-response study of intravenous m -chlorophenylpiperazine in normal subjects [Elektronische Daten] [Oren Kalus, Scott Wetzler, René Kahn, Gregory Asnis, Herman van Praag] A placebo-controlled dose-response study of the direct serotonin receptor agonistm-chlorophenylpiperazine (MCPP), intravenously infused over 90 s in 0.06 and 0.08 mg/kg doses, was conducted in nine normal male subjects. Cortisol, prolactin, MCPP serum levels and behavioral responses were measured over a 210-min period. Both doses caused significant cortisol and prolactin release and were associated with significantly greater behavioral effects as compared to placebo. Though the two doses were associated with different MCPP serum levels, they did not significantly differ in their hormonal and behavioral effects. Springer-Verlag, 1992 MCPP nationallicence Serotonin nationallicence Dose-response nationallicence Intravenous nationallicence Kalus Oren Department of Psychiatry, Albert Einstein College of Medicine, Montefiore Medical Center, USA aut Wetzler Scott Department of Psychiatry, Albert Einstein College of Medicine, Montefiore Medical Center, USA aut Kahn René Department of Psychiatry, Albert Einstein College of Medicine, Montefiore Medical Center, USA aut Asnis Gregory Department of Psychiatry, Albert Einstein College of Medicine, Montefiore Medical Center, USA aut van Praag Herman Department of Psychiatry, Albert Einstein College of Medicine, Montefiore Medical Center, USA aut Psychopharmacology Springer-Verlag 106/3(1992-03-01), 388-390 0033-3158 106:3<388 1992 106 213 https://doi.org/10.1007/BF02245423 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02245423 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kalus Oren Department of Psychiatry, Albert Einstein College of Medicine, Montefiore Medical Center, USA aut NATIONALLICENCE 700 1- Wetzler Scott Department of Psychiatry, Albert Einstein College of Medicine, Montefiore Medical Center, USA aut NATIONALLICENCE 700 1- Kahn René Department of Psychiatry, Albert Einstein College of Medicine, Montefiore Medical Center, USA aut NATIONALLICENCE 700 1- Asnis Gregory Department of Psychiatry, Albert Einstein College of Medicine, Montefiore Medical Center, USA aut NATIONALLICENCE 700 1- van Praag Herman Department of Psychiatry, Albert Einstein College of Medicine, Montefiore Medical Center, USA aut NATIONALLICENCE 773 0- Psychopharmacology Springer-Verlag 106/3(1992-03-01), 388-390 0033-3158 106:3<388 1992 106 213 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer