caa a22 4500 469121556 CHVBK 20180323133140.0 cr unu---uuuuu 170328e19920201xx s 000 0 eng 10.1007/BF02246229 doi (NATIONALLICENCE)springer-10.1007/BF02246229 Interactions of moclobemide with concomitantly administered medication: evidence from pharmacological and clinical studies [Elektronische Daten] [R. Amrein, T. Güntert, J. Dingemanse, T. Lorscheid, M. Stabl, W. Schmid-Burgk] Interactions may occur on pharmacological or pharmacokinetic grounds. Both types of interactions are discussed in relationship with the pharmacological and pharmacokinetic data of moclobemide, a reversible MAO-inhibitor. A variety of interaction studies either designed more specifically as kinetic or as dynamic studies have been performed with moclobemide. The results of these studies are presented. In view of these results as well as in view of data stemming from clinical trials it can be concluded that apart from interactions with cimetidine and pethidine, moclobemide has been shown to be devoid of relevant interactions. Springer-Verlag, 1992 Moclobemide nationallicence Interactions nationallicence Pharmacokinetics nationallicence Pharmacological data nationallicence Amrein R. Department of Clinical Research, F. Hoffmann-La Roche Ltd, CH-4002, Basel, Switzerland aut Güntert T. Department of Clinical Research, F. Hoffmann-La Roche Ltd, CH-4002, Basel, Switzerland aut Dingemanse J. Department of Clinical Research, F. Hoffmann-La Roche Ltd, CH-4002, Basel, Switzerland aut Lorscheid T. Department of Clinical Research, F. Hoffmann-La Roche Ltd, CH-4002, Basel, Switzerland aut Stabl M. Department of Clinical Research, F. Hoffmann-La Roche Ltd, CH-4002, Basel, Switzerland aut Schmid-Burgk W. Department of Clinical Research, F. Hoffmann-La Roche Ltd, CH-4002, Basel, Switzerland aut Psychopharmacology Springer-Verlag 106(1992-02-01), S24-S31 0033-3158 106<S24 1992 106 213 https://doi.org/10.1007/BF02246229 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02246229 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Amrein R. Department of Clinical Research, F. Hoffmann-La Roche Ltd, CH-4002, Basel, Switzerland aut NATIONALLICENCE 700 1- Güntert T. Department of Clinical Research, F. Hoffmann-La Roche Ltd, CH-4002, Basel, Switzerland aut NATIONALLICENCE 700 1- Dingemanse J. Department of Clinical Research, F. Hoffmann-La Roche Ltd, CH-4002, Basel, Switzerland aut NATIONALLICENCE 700 1- Lorscheid T. Department of Clinical Research, F. Hoffmann-La Roche Ltd, CH-4002, Basel, Switzerland aut NATIONALLICENCE 700 1- Stabl M. Department of Clinical Research, F. Hoffmann-La Roche Ltd, CH-4002, Basel, Switzerland aut NATIONALLICENCE 700 1- Schmid-Burgk W. Department of Clinical Research, F. Hoffmann-La Roche Ltd, CH-4002, Basel, Switzerland aut NATIONALLICENCE 773 0- Psychopharmacology Springer-Verlag 106(1992-02-01), S24-S31 0033-3158 106<S24 1992 106 213 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer