caa a22 4500 469122250 CHVBK 20180323133142.0 cr unu---uuuuu 170328e19920601xx s 000 0 eng 10.1007/BF02801984 doi (NATIONALLICENCE)springer-10.1007/BF02801984 Subjective correlates of cigarette-smoking-induced elevations of peripheral beta-endorphin and cortisol [Elektronische Daten] [David Gilbert, Charles Meliska, Cedric Williams, Robert Jensen] Two experiments assessed subjective and hormonal effects of smoking cigarettes with three different nicotine deliveries. In experiment 1, 12 males smoked two cigarettes on three different occasions: (1) nicotine-free; (2) their own brand (1.0 mg FTC-estimated nicotine delivery); or (3) 2.4 mg FTC nicotine cigarettes. In experiment 2, 12 males smoked cigarettes of comparable nicotine yield using a quantified smoke delivery system (QSDS). Blood was sampled 2 min after each cigarette completion. Relative to nicotine-free smoking, plasma beta-endorphin (BE) and serum cortisol concentrations increased after quasi-ad libitum smoking of 2.4 mg, but not after 1.0 mg nicotine cigarettes. Self-reported malaise (nausea, sickness, and unpleasantness) also increased after smoking 2.4 mg nicotine cigarettes; subjective distress was correlated with changes in blood BE and cortisol, Smoking 1.0 mg cigarettes did not increase BE or cortisol, or subjective distress. QSDS smoking produced hormonal and subjective effects similar to quasi-ad libitum smoking; however, correlations between neuromodulator concentrations and mood were non-significant. These findings suggest that the elevated levels of plasma BE and cortisol reported in some smoking studies may not be characteristic effects of normal smoking. Springer-Verlag, 1992 Nicotine nationallicence Smoking nationallicence Beta-endorphin nationallicence Cortisol nationallicence Nausea nationallicence Affect nationallicence Reinforcement nationallicence Neuromodulators nationallicence Gilbert David Department of Psychology, Southern Illinois University at Carbondale, 62901-6502, Carbondale, IL, USA aut Meliska Charles Department of Psychology, Southern Illinois University at Carbondale, 62901-6502, Carbondale, IL, USA aut Williams Cedric Department of Psychology, Southern Illinois University at Carbondale, 62901-6502, Carbondale, IL, USA aut Jensen Robert Department of Psychology, Southern Illinois University at Carbondale, 62901-6502, Carbondale, IL, USA aut Psychopharmacology Springer-Verlag 106/2(1992-06-01), 275-281 0033-3158 106:2<275 1992 106 213 https://doi.org/10.1007/BF02801984 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02801984 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gilbert David Department of Psychology, Southern Illinois University at Carbondale, 62901-6502, Carbondale, IL, USA aut NATIONALLICENCE 700 1- Meliska Charles Department of Psychology, Southern Illinois University at Carbondale, 62901-6502, Carbondale, IL, USA aut NATIONALLICENCE 700 1- Williams Cedric Department of Psychology, Southern Illinois University at Carbondale, 62901-6502, Carbondale, IL, USA aut NATIONALLICENCE 700 1- Jensen Robert Department of Psychology, Southern Illinois University at Carbondale, 62901-6502, Carbondale, IL, USA aut NATIONALLICENCE 773 0- Psychopharmacology Springer-Verlag 106/2(1992-06-01), 275-281 0033-3158 106:2<275 1992 106 213 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer