caa a22 4500 46912251X CHVBK 20180323133143.0 cr unu---uuuuu 170328e19921101xx s 000 0 eng 10.1007/BF02368606 doi (NATIONALLICENCE)springer-10.1007/BF02368606 Numerical simulation of aerosol particle transport by oscillating flow in respiratory airways [Elektronische Daten] [James Briant, Duane Frank, Anthony James, L. Eyler] Particle transport by oscillating flow in a tapered channel or in a tapered tube was computed from the complete equations of motion. These geometries represent a simplified model of the divergent flow field of the mammalian bronchial tree. The computed deformation profile of a line of particles, transported by the oscillatory motion, was compared with prior experimental results and analytical calculations. All three methods agree that there is transport in the divergent direction of the tube by an axial stream of steady drift in the core for moderately high frequency of oscillation (Womersley parameter in the range of 1 to 10). Bidirectional flow is established by an annular stream in the convergent direction, with no net flow on integral cycles of the oscillating fluid. At higher frequency, however, the steady stream transforms to a different shape in the tapered tube, with transport in the divergent direction nearer the walls of the tube, rather than in the core. Transport by the continuing streams with oscillatory ventilation of the respiratory tract should deliver medicinal aerosols of low intrinsic particle mobility to the peripheral regions of the lungs. Pergamon Press Ltd., 1992 High-frequency oscillatory ventilation nationallicence Mammalian bronchial tree nationallicence computational fluid mechanics nationallicence Briant James Health Physics Department, Pacific Northwest Laboratory, 99352, Richland, WA aut Frank Duane Health Physics Department, Pacific Northwest Laboratory, 99352, Richland, WA aut James Anthony Health Physics Department, Pacific Northwest Laboratory, 99352, Richland, WA aut Eyler L. Energy Sciences Department, Pacific Northwest Laboratory, 99352, Battelle Boulevard Richland, WA aut Annals of Biomedical Engineering Kluwer Academic Publishers 20/6(1992-11-01), 573-581 0090-6964 20:6<573 1992 20 10439 https://doi.org/10.1007/BF02368606 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02368606 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Briant James Health Physics Department, Pacific Northwest Laboratory, 99352, Richland, WA aut NATIONALLICENCE 700 1- Frank Duane Health Physics Department, Pacific Northwest Laboratory, 99352, Richland, WA aut NATIONALLICENCE 700 1- James Anthony Health Physics Department, Pacific Northwest Laboratory, 99352, Richland, WA aut NATIONALLICENCE 700 1- Eyler L. Energy Sciences Department, Pacific Northwest Laboratory, 99352, Battelle Boulevard Richland, WA aut NATIONALLICENCE 773 0- Annals of Biomedical Engineering Kluwer Academic Publishers 20/6(1992-11-01), 573-581 0090-6964 20:6<573 1992 20 10439 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer