caa a22 4500 469127163 CHVBK 20180323133153.0 cr unu---uuuuu 170328e19920301xx s 000 0 eng 10.1007/BF02357230 doi (NATIONALLICENCE)springer-10.1007/BF02357230 Trypanosomiasis control in Boran cattle in Kenya: A comparison between chemoprophylaxis and a parasite detection and intravenous treatment method using isometamidium chloride [Elektronische Daten] [S. Münstermann, R. Mbura, S. Maloo, K. Löhr] Summary: Two methods of trypanosome control in Boran cattle kept under very high trypanosomiasis risk were compared: the traditional intramuscular isometamidium chloride prophylaxis with a parasite detection and intravenous isometamidium chloride treatment method. The results were related to a control group under diminazene aceturate treatment. Isometamidium chloride at 0.25 mg/kg as routinely used by the ranch was of little benefit by either method, with breakthrough infections occurring as early as one week after treatment. When isometamidium chloride at 1 mg/kg was used, the curative intravenous method appeared to be superior to the intramuscular prophylaxis with regard to cost of drugs and to a 31% higher weight gain over a 30 week period. Weekly infection rates in the intravenous group decreased over time, despite an increasing trypanosomiasis challenge, with a mean interval of 6.4 weeks between treatments as compared with 4.3 weeks in a diminazene aceturate control group. It was concluded that isometamidium chloride given intravenously had not only a very good therapeutic but also a considerable prophylactic effect of not less than four weeks. Centre for Tropical Veterinary Medicine, University of Edinburgh, 1992 Münstermann S. Witu Veterinary Laboratory, PO, Witu/Lamu, Kenya aut Mbura R. Witu Veterinary Laboratory, PO, Witu/Lamu, Kenya aut Maloo S. Veterinary Investigation Laboratory, PO Box 204, Mariakani, Kenya aut Löhr K. Veterinary Investigation Laboratory, PO Box 204, Mariakani, Kenya aut Tropical Animal Health and Production Kluwer Academic Publishers 24/1(1992-03-01), 17-27 0049-4747 24:1<17 1992 24 11250 https://doi.org/10.1007/BF02357230 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02357230 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Münstermann S. Witu Veterinary Laboratory, PO, Witu/Lamu, Kenya aut NATIONALLICENCE 700 1- Mbura R. Witu Veterinary Laboratory, PO, Witu/Lamu, Kenya aut NATIONALLICENCE 700 1- Maloo S. Veterinary Investigation Laboratory, PO Box 204, Mariakani, Kenya aut NATIONALLICENCE 700 1- Löhr K. Veterinary Investigation Laboratory, PO Box 204, Mariakani, Kenya aut NATIONALLICENCE 773 0- Tropical Animal Health and Production Kluwer Academic Publishers 24/1(1992-03-01), 17-27 0049-4747 24:1<17 1992 24 11250 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer