caa a22 4500 469128461 CHVBK 20180323133157.0 cr unu---uuuuu 170328e19920901xx s 000 0 eng 10.1007/BF00573503 doi (NATIONALLICENCE)springer-10.1007/BF00573503 Atrial natriuretic factor and right atrial pressure in patients undergoing chronic haemodialysis [Elektronische Daten] [G. Tonolo, V. Scardaccio, M. La Rocca, A. Soro, M. Melis, C. Troffa, A. Pazzola, G. Sabino, G. Patteri, N. Glorioso, G. Realdi] To quantitate the mutual relationship between central venous pressure (CVP) and circulating atrial natriuretic factor (ANF) during haemodialysis, nine end-stage renal failure patients on chronic haemodialysis underwent ultrafiltration (UF) and biochemical correction (3 h) separated by 1 h (no dialysis, ND). During UF CVP and circulating ANF decreased significantly in all patients from basal levels (0.5±1.0 vs 5.4±2.0 mmHg and 58±16 vs 95±19 pmol/l respectively,P<0.01 for both), while microhaematocrit increased significantly (29.5±1 vs 26.0±1%,P<0.01). During ND, CVP and ANF rose significantly (P<0.05 for both) in seven of the nine patients, while microhaematocrit returned towards basal values. In two patients CVP did not change during ND and circulating ANF remained unchanged. A significant correlation between CVP and circulating ANF was found (end-basal to end-UF,r=0.72,P<0.05; end-UF to end-ND,r=0.77,P=0.025;n=7). As expected, during biochemical correction plasma creatinine and K+ decreased significantly and consistently in all the patients (from 875±74 to 400±56 μmol/l and from 4.7±0.07 to 4.0±0.04 mEq/l, respectively;n=9,P<0.01 for both) as did body weight during UF (65.6±7 vs 67±5 kg;n=9,P<0.05). No significant changes were seen for systolic and diastolic blood pressure, heart rate and plasma renin activity at any time. Our data provide further evidence that the regulation of circulating ANF is synchronized with changes in CVP. They also quantitate the mutual relationship between CVP and ANF in end-stage renal failure. Springer-Verlag, 1992 Atrial natriuretic peptide nationallicence Central venous pressure nationallicence Tonolo G. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut Scardaccio V. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut La Rocca M. Dialysis Unit, Tempio Pausania General Hospital, Tempio Pausania, Italy aut Soro A. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut Melis M. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut Troffa C. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut Pazzola A. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut Sabino G. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut Patteri G. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut Glorioso N. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut Realdi G. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut Acta Diabetologica Springer-Verlag 29/3-4(1992-09-01), 273-277 0940-5429 29:3-4<273 1992 29 592 https://doi.org/10.1007/BF00573503 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00573503 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tonolo G. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut NATIONALLICENCE 700 1- Scardaccio V. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut NATIONALLICENCE 700 1- La Rocca M. Dialysis Unit, Tempio Pausania General Hospital, Tempio Pausania, Italy aut NATIONALLICENCE 700 1- Soro A. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut NATIONALLICENCE 700 1- Melis M. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut NATIONALLICENCE 700 1- Troffa C. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut NATIONALLICENCE 700 1- Pazzola A. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut NATIONALLICENCE 700 1- Sabino G. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut NATIONALLICENCE 700 1- Patteri G. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut NATIONALLICENCE 700 1- Glorioso N. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut NATIONALLICENCE 700 1- Realdi G. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut NATIONALLICENCE 773 0- Acta Diabetologica Springer-Verlag 29/3-4(1992-09-01), 273-277 0940-5429 29:3-4<273 1992 29 592 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer