caa a22 4500 469128496 CHVBK 20180323133157.0 cr unu---uuuuu 170328e19920901xx s 000 0 eng 10.1007/BF00573498 doi (NATIONALLICENCE)springer-10.1007/BF00573498 Lipid pattern, apolipoproteins A1 and B and lipoprotein (a) in type 1 diabetic patients with microalbuminuria [Elektronische Daten] [M. Maioli, G. Tonolo, G. Arca, P. Brizzi, G. Cherchi, M. Ciccarese, A. Pacifico, G. Realdi] The plasma lipid changes commonly observed in patients with diabetic nephropathy may play a major role in determining the increased cardiovascular risk in these patients. Contrasting results have been reported on the patterns of lipids and lipoproteins in diabetic subjects with microalbuminuria. We examined 20 patients with type 1 (insulin-dependent) diabetes who had a urinary albumin excretion >30 mg/24 h (11 males and 9 females, age range 16-45 years, mean diabetes duration 11.7 years) and 20 type 1 diabetic patients without microalbuminuria matched for sex, age, diabetes duration, daily insulin requirement and degree of metabolic control. In all patients we measured plasma total cholesterol, highdensity lipoprotein (HDL)-cholesterol, triglycerides, apolipoproteins A1 and B and lipoprotein (a) [Lp(a)]. No significant differences were found for any parameter between subjects with a urinary albumin excretion <20 mg/ 24 h and microalbuminuric patients. Moreover in nondiabetic controls the levels of plasma Lp(a) and of the other parameters measured were not significantly different from those of the two diabetic groups. Our results suggest that in type 1 diabetic patients with fairly good glycaemic control microalbuminuria is not associated with significant changes in the lipoprotein pattern. Springer-Verlag, 1992 Lp(a) nationallicence Type 1 (insulin-dependent) diabetes nationallicence Urinary albumin excretion nationallicence Maioli M. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut Tonolo G. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut Arca G. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut Brizzi P. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut Cherchi G. Cattedra di Analisi Biologiche, Facoltà di Scienze, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut Ciccarese M. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut Pacifico A. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut Realdi G. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut Acta Diabetologica Springer-Verlag 29/3-4(1992-09-01), 246-249 0940-5429 29:3-4<246 1992 29 592 https://doi.org/10.1007/BF00573498 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00573498 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Maioli M. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut NATIONALLICENCE 700 1- Tonolo G. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut NATIONALLICENCE 700 1- Arca G. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut NATIONALLICENCE 700 1- Brizzi P. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut NATIONALLICENCE 700 1- Cherchi G. Cattedra di Analisi Biologiche, Facoltà di Scienze, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut NATIONALLICENCE 700 1- Ciccarese M. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut NATIONALLICENCE 700 1- Pacifico A. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut NATIONALLICENCE 700 1- Realdi G. Istituto di Clinica Medica, University of Sassari, Viale San Pietro 8, I-07100, Sassari, Italy aut NATIONALLICENCE 773 0- Acta Diabetologica Springer-Verlag 29/3-4(1992-09-01), 246-249 0940-5429 29:3-4<246 1992 29 592 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer