caa a22 4500 475742338 CHVBK 20180406123503.0 cr unu---uuuuu 170329e20000201xx s 000 0 eng 10.1007/s002400050006 doi (NATIONALLICENCE)springer-10.1007/s002400050006 Morphometric analysis of symptomatic benign prostatic hyperplasia with and without bladder outlet obstruction [Elektronische Daten] [O. Ichiyanagi, I. Sasagawa, M. Ishigooka, Y. Suzuki, T. Nakada] To investigate the histological features of benign prostatic hyperplasia (BPH) with and without bladder outlet obstruction (BOO), 32 patients with symptomatic BPH, 22 with BOO and ten without BOO, were studied. The area density of smooth muscle, fibrous tissue, glandular epithelium, and glandular lumen in BPH adenoma resected by transurethral surgery was estimated using morphometric analysis. No differences were found in the area density of stromal and glandular components between the two groups. In the glandular component, neither the epithelium nor lumen differed between the two groups. However, the area density of smooth muscle in the obstructed group showed a decrease compared to that in the unobstructed group (P < 0.01). We conclude that a decreased proportion of smooth muscle in BPH adenoma may play an important role in BOO. Springer-Verlag Berlin Heidelberg, 2000 Key words Prostatic hyperplasia nationallicence Morphometry nationallicence Bladder outlet obstruction nationallicence Smooth muscle nationallicence Ichiyanagi O. Department of Urology, Yamagata University School of Medicine, 2-2-2 Iidanishi, Yamagata-shi, Yamagata 990-9585, Japan e-mail: isasaga@med.id.yamagata-u.ac.jp, Fax: 81-236-242837, JP aut Sasagawa I. Department of Urology, Yamagata University School of Medicine, 2-2-2 Iidanishi, Yamagata-shi, Yamagata 990-9585, Japan e-mail: isasaga@med.id.yamagata-u.ac.jp, Fax: 81-236-242837, JP aut Ishigooka M. Department of Urology, Yamagata University School of Medicine, 2-2-2 Iidanishi, Yamagata-shi, Yamagata 990-9585, Japan e-mail: isasaga@med.id.yamagata-u.ac.jp, Fax: 81-236-242837, JP aut Suzuki Y. Department of Urology, Yamagata University School of Medicine, 2-2-2 Iidanishi, Yamagata-shi, Yamagata 990-9585, Japan e-mail: isasaga@med.id.yamagata-u.ac.jp, Fax: 81-236-242837, JP aut Nakada T. Department of Urology, Yamagata University School of Medicine, 2-2-2 Iidanishi, Yamagata-shi, Yamagata 990-9585, Japan e-mail: isasaga@med.id.yamagata-u.ac.jp, Fax: 81-236-242837, JP aut https://doi.org/10.1007/s002400050006 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002400050006 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ichiyanagi O. Department of Urology, Yamagata University School of Medicine, 2-2-2 Iidanishi, Yamagata-shi, Yamagata 990-9585, Japan e-mail: isasaga@med.id.yamagata-u.ac.jp, Fax: 81-236-242837, JP aut NATIONALLICENCE 700 1- Sasagawa I. Department of Urology, Yamagata University School of Medicine, 2-2-2 Iidanishi, Yamagata-shi, Yamagata 990-9585, Japan e-mail: isasaga@med.id.yamagata-u.ac.jp, Fax: 81-236-242837, JP aut NATIONALLICENCE 700 1- Ishigooka M. Department of Urology, Yamagata University School of Medicine, 2-2-2 Iidanishi, Yamagata-shi, Yamagata 990-9585, Japan e-mail: isasaga@med.id.yamagata-u.ac.jp, Fax: 81-236-242837, JP aut NATIONALLICENCE 700 1- Suzuki Y. Department of Urology, Yamagata University School of Medicine, 2-2-2 Iidanishi, Yamagata-shi, Yamagata 990-9585, Japan e-mail: isasaga@med.id.yamagata-u.ac.jp, Fax: 81-236-242837, JP aut NATIONALLICENCE 700 1- Nakada T. Department of Urology, Yamagata University School of Medicine, 2-2-2 Iidanishi, Yamagata-shi, Yamagata 990-9585, Japan e-mail: isasaga@med.id.yamagata-u.ac.jp, Fax: 81-236-242837, JP aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer