caa a22 4500 475742710 CHVBK 20180406123504.0 cr unu---uuuuu 170329e20000801xx s 000 0 eng 10.1007/s002400000125 doi (NATIONALLICENCE)springer-10.1007/s002400000125 First experience with gamma probe guided sentinel lymph node surgery in penile cancer [Elektronische Daten] [Friedhelm Wawroschek, Harry Vogt, Dieter Bachter, Dorothea Weckermann, Michael Hamm, Rolf Harzmann] Because of the curative approach, the detection of lymph node metastases in squamous cell carcinoma (SCC) of the penis is of significant clinical relevance. Sentinel lymph node (SLN) identification by means of lymphangiography has been proven to be insufficiently safe. However, the high morbidity of inguinal lymphadenectomy and the considerable individual variability regarding the location of lymph node metastases justify the necessity of a technique that enables the identification of SLNs. Since 1998, SLNs have been intraoperatively identified and selectively dissected, after peritumoral injection of technetium-99m nanocolloid and using lymphoscintigraphy, in three patients (one with malignant melanoma and two with SCC). At least one SLN could be detected in each patient. The maximum surgical time was 30 min. There were no severe complications. Lymph node metastases did not occur in any patient. Upon a mean follow-up of 10 months, all patients are currently free of tumor. Owing to the long-term results of sentinel lymphadenectomy in malignant melanoma of other locations and our preliminary results with respect to penile carcinoma, we consider the current method appropriate as the only primary operation for lymph node staging in early stages and, in combination with modified inguinal lymphadenectomy, in locally advanced stages. Springer-Verlag Berlin Heidelberg, 2000 Key words Penile neoplasms nationallicence Lymph node excision nationallicence Radio nuclide imaging nationallicence Wawroschek Friedhelm Department of Urology, Zentralklinikum Augsburg, Stenglinstr. 2, 86156 Augsburg, Germany Tel.: +49-821-4002848; Fax: +49-821-4004578, DE aut Vogt Harry Department of Nuclear Medicine, Zentralklinikum Augsburg, Augsburg, Germany, DE aut Bachter Dieter Department of Dermatology, Zentralklinikum Augsburg, Augsburg, Germany, DE aut Weckermann Dorothea Department of Urology, Zentralklinikum Augsburg, Stenglinstr. 2, 86156 Augsburg, Germany Tel.: +49-821-4002848; Fax: +49-821-4004578, DE aut Hamm Michael Department of Urology, Zentralklinikum Augsburg, Stenglinstr. 2, 86156 Augsburg, Germany Tel.: +49-821-4002848; Fax: +49-821-4004578, DE aut Harzmann Rolf Department of Urology, Zentralklinikum Augsburg, Stenglinstr. 2, 86156 Augsburg, Germany Tel.: +49-821-4002848; Fax: +49-821-4004578, DE aut https://doi.org/10.1007/s002400000125 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002400000125 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wawroschek Friedhelm Department of Urology, Zentralklinikum Augsburg, Stenglinstr. 2, 86156 Augsburg, Germany Tel.: +49-821-4002848; Fax: +49-821-4004578, DE aut NATIONALLICENCE 700 1- Vogt Harry Department of Nuclear Medicine, Zentralklinikum Augsburg, Augsburg, Germany, DE aut NATIONALLICENCE 700 1- Bachter Dieter Department of Dermatology, Zentralklinikum Augsburg, Augsburg, Germany, DE aut NATIONALLICENCE 700 1- Weckermann Dorothea Department of Urology, Zentralklinikum Augsburg, Stenglinstr. 2, 86156 Augsburg, Germany Tel.: +49-821-4002848; Fax: +49-821-4004578, DE aut NATIONALLICENCE 700 1- Hamm Michael Department of Urology, Zentralklinikum Augsburg, Stenglinstr. 2, 86156 Augsburg, Germany Tel.: +49-821-4002848; Fax: +49-821-4004578, DE aut NATIONALLICENCE 700 1- Harzmann Rolf Department of Urology, Zentralklinikum Augsburg, Stenglinstr. 2, 86156 Augsburg, Germany Tel.: +49-821-4002848; Fax: +49-821-4004578, DE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer