caa a22 4500 475742818 CHVBK 20180406123504.0 cr unu---uuuuu 170329e20001001xx s 000 0 eng 10.1007/s002400000119 doi (NATIONALLICENCE)springer-10.1007/s002400000119 Immunohistochemical and molecular analysis in recurrent urethral stricture [Elektronische Daten] [G. Morgia, A. Saita, M. Falsaperla, A. Spampinato, M. Motta, S. Cordaro] The authors have analyzed the most recent additions to the literature of immunohistochemical and molecular assessment of acquired urethral strictures and report on their data obtained in a selected clinical series. Innovative immunohistochemical studies in patients presenting with plurirecurrent symptoms suggest that urethral mesenchymal changes caused by tissue de-epithelialization may be the underlying cause of stricture. This condition may be congenital or acquired. It may determine aberrant connective tissue formation induced by abnormal fibroblastic activation with formation of over abundant hyperdense collagen scar tissue. Springer-Verlag Berlin Heidelberg, 2000 Key words Urethral strictures nationallicence Mesenchymal disease nationallicence Morgia G. Via Fisichelli 32, 95037 S.G. La Punta (CT), Italy e-mail: morgia@mbox.unict.it Tel.: +39-95-7412868; Fax.: +39-95-7513576, IT aut Saita A. Department of Urology, University of Catania, Catania, Italy, IT aut Falsaperla M. Department of Urology, University of Catania, Catania, Italy, IT aut Spampinato A. Department of Urology, University of Catania, Catania, Italy, IT aut Motta M. Department of Urology, University of Catania, Catania, Italy, IT aut Cordaro S. Histopathology Unit, M. Ascoli Hospital, Catania, Italy, IT aut https://doi.org/10.1007/s002400000119 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002400000119 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Morgia G. Via Fisichelli 32, 95037 S.G. La Punta (CT), Italy e-mail: morgia@mbox.unict.it Tel.: +39-95-7412868; Fax.: +39-95-7513576, IT aut NATIONALLICENCE 700 1- Saita A. Department of Urology, University of Catania, Catania, Italy, IT aut NATIONALLICENCE 700 1- Falsaperla M. Department of Urology, University of Catania, Catania, Italy, IT aut NATIONALLICENCE 700 1- Spampinato A. Department of Urology, University of Catania, Catania, Italy, IT aut NATIONALLICENCE 700 1- Motta M. Department of Urology, University of Catania, Catania, Italy, IT aut NATIONALLICENCE 700 1- Cordaro S. Histopathology Unit, M. Ascoli Hospital, Catania, Italy, IT aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer