caa a22 4500 475742842 CHVBK 20180406123504.0 cr unu---uuuuu 170329e20001001xx s 000 0 eng 10.1007/s002400000122 doi (NATIONALLICENCE)springer-10.1007/s002400000122 Testicular focal atrophy - tubular blockade as partial degeneration of the tubule [Elektronische Daten] [Christian Reek, Haide Breucker, Adolf-F. Holstein] This study investigated whether focal atrophy is a degenerative process of a whole tubule or tubular blockade as partial intratesticular degeneration. Serial section analyses of testicular tissue from 19 men with different andrologic diseases were examined. From every fifth section of any series, defined areas were viewed under a light microscope, and tubule sections were drawn. Three-dimensional reconstructions were made from these materials. Reconstructions of the seminiferous tubules showed tubular blockade as partial degeneration of the tubules. Transition from an intact portion to a blockade was accompanied by an increase in the thickness of the lamina propria. The blockade was a cell cord that contained Sertoli cells and, at most, spermatogonia, or it was a completely atrophied tubule, a so-called tubular scar. In a given tubule, defined areas of atrophy and areas of spermatogenic activity were both found. Occurrence of tubular blockade increased with age. Serial section analyses of testicular tissue showed tubular blockade as the partial degeneration of seminiferous tubules. In focal atrophy, a given tubule can have defined areas of atrophy and areas of spermatogenic activity. Springer-Verlag Berlin Heidelberg, 2000 Key words Testis nationallicence Tubule nationallicence Oligozoospermia nationallicence Testicular focal atrophy nationallicence seminiferous tubular blockade as partial tubular degeneration nationallicence Reek Christian Department of Urology, University of Hamburg, Martinistrasse 52, 20246 Hamburg, Germany Tel.: +49-40-42803-4462; Fax: +49-40-42803-9022, DE aut Breucker Haide Anatomisches Institut, Martinistrasse 52, 20246 Hamburg, Germany, DE aut Holstein Adolf-F Anatomisches Institut, Martinistrasse 52, 20246 Hamburg, Germany, DE aut https://doi.org/10.1007/s002400000122 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002400000122 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Reek Christian Department of Urology, University of Hamburg, Martinistrasse 52, 20246 Hamburg, Germany Tel.: +49-40-42803-4462; Fax: +49-40-42803-9022, DE aut NATIONALLICENCE 700 1- Breucker Haide Anatomisches Institut, Martinistrasse 52, 20246 Hamburg, Germany, DE aut NATIONALLICENCE 700 1- Holstein Adolf-F Anatomisches Institut, Martinistrasse 52, 20246 Hamburg, Germany, DE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer