caa a22 4500 47574442X CHVBK 20180406123509.0 cr unu---uuuuu 170329e20001101xx s 000 0 eng 10.1023/A:1007181600453 doi (NATIONALLICENCE)springer-10.1023/A:1007181600453 Oligosaccharides as Immunodeterminants of Erythropoietin for Two Sets of Anti-Carbohydrate Antibodies [Elektronische Daten] [John Pazur, Philip Jensen, Allen Murray] Antibodies directed against recombinant erythropoietin have been obtained by immunization of rabbits with the hormone in Freund's complete adjuvant. Two sets of antibodies are present in the serum of the immunized rabbits. The results of oxidation of the erythropoietin with periodate, inhibition of the antibodies with the structural monosaccharide residues of the hormone, and reaction of the antibodies with lectins of known carbohydrate specificity have established the antibodies to be anti-carbohydrate antibodies. These antibodies may be of value as tracking agents for some diseases and should be useful for detecting abuses of the hormone in enhancing performance in athletic competitions. Plenum Publishing Corporation, 2000 Erythropoietin nationallicence glycoprotein nationallicence anti-carbohydrate antibodies nationallicence immunodeterminants nationallicence oligosaccharides nationallicence Pazur John Department of Biochemistry and Molecular Biology, The Pennsylvania State University, 16802, University Park, Pennsylvania aut Jensen Philip Department of Plant Pathology, The Pennsylvania State University, 16802, University Park, Pennsylvania aut Murray Allen 92614, Irvine, California aut Journal of Protein Chemistry Kluwer Academic Publishers-Plenum Publishers 19/8(2000-11-01), 631-635 0277-8033 19:8<631 2000 19 10930 https://doi.org/10.1023/A:1007181600453 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1007181600453 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Pazur John Department of Biochemistry and Molecular Biology, The Pennsylvania State University, 16802, University Park, Pennsylvania aut NATIONALLICENCE 700 1- Jensen Philip Department of Plant Pathology, The Pennsylvania State University, 16802, University Park, Pennsylvania aut NATIONALLICENCE 700 1- Murray Allen 92614, Irvine, California aut NATIONALLICENCE 773 0- Journal of Protein Chemistry Kluwer Academic Publishers-Plenum Publishers 19/8(2000-11-01), 631-635 0277-8033 19:8<631 2000 19 10930 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer