caa a22 4500 475746686 CHVBK 20180406123515.0 cr unu---uuuuu 170329e20000901xx s 000 0 eng 10.1007/s002840010121 doi (NATIONALLICENCE)springer-10.1007/s002840010121 Antibacterial Carbohydrate Monoesters Suppressing Cell Growth of Streptococcus mutans in the Presence of Sucrose [Elektronische Daten] [Takashi Watanabe, Shihoko Katayama, Mayu Matsubara, Yoichi Honda, Masaaki Kuwahara] The growth-inhibitory effect of 23 carbohydrate monoesters synthesized by lipases and proteases were assayed to obtain antibacterial agents that suppress the cell growth of Streptococcus mutans. Among the carbohydrate esters synthesized, galactose and fructose laurates showed the highest growth-inhibitory effect, while the other analogs of hexose laurates showed no antibacterial activity, indicating that configuration of the hydroxyl group in carbohydrate moiety markedly affects the antibacterial activity. The cell growth of S. mutans was suppressed by fructose laurates even in the presence of sucrose. Thus, enzymatic synthesis of carbohydrate esters with different core structures has great potential for developing antibacterial agents applicable to food additives. Springer-Verlag New York Inc., 2000 Watanabe Takashi Laboratory of Biomass Conversion, Wood Research Institute, Kyoto University, Gokasho, Uji, Kyoto 611-0011, Japan, JP aut Katayama Shihoko Laboratory of Biomass Conversion, Wood Research Institute, Kyoto University, Gokasho, Uji, Kyoto 611-0011, Japan, JP aut Matsubara Mayu Laboratory of Biomass Conversion, Wood Research Institute, Kyoto University, Gokasho, Uji, Kyoto 611-0011, Japan, JP aut Honda Yoichi Laboratory of Biomass Conversion, Wood Research Institute, Kyoto University, Gokasho, Uji, Kyoto 611-0011, Japan, JP aut Kuwahara Masaaki Laboratory of Biomass Conversion, Wood Research Institute, Kyoto University, Gokasho, Uji, Kyoto 611-0011, Japan, JP aut https://doi.org/10.1007/s002840010121 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002840010121 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Watanabe Takashi Laboratory of Biomass Conversion, Wood Research Institute, Kyoto University, Gokasho, Uji, Kyoto 611-0011, Japan, JP aut NATIONALLICENCE 700 1- Katayama Shihoko Laboratory of Biomass Conversion, Wood Research Institute, Kyoto University, Gokasho, Uji, Kyoto 611-0011, Japan, JP aut NATIONALLICENCE 700 1- Matsubara Mayu Laboratory of Biomass Conversion, Wood Research Institute, Kyoto University, Gokasho, Uji, Kyoto 611-0011, Japan, JP aut NATIONALLICENCE 700 1- Honda Yoichi Laboratory of Biomass Conversion, Wood Research Institute, Kyoto University, Gokasho, Uji, Kyoto 611-0011, Japan, JP aut NATIONALLICENCE 700 1- Kuwahara Masaaki Laboratory of Biomass Conversion, Wood Research Institute, Kyoto University, Gokasho, Uji, Kyoto 611-0011, Japan, JP aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer