caa a22 4500 475747054 CHVBK 20180406123516.0 cr unu---uuuuu 170329e20000801xx s 000 0 eng 10.1007/s002840010102 doi (NATIONALLICENCE)springer-10.1007/s002840010102 Variation in sic Gene Encoding Complement-Inhibiting Protein of Streptococcus pyogenes Serotype M1 Isolates in Japan [Elektronische Daten] [Toshiyuki Murase, Yosuke Kameoka, Rieko Suzuki, Shiro Yamai] DNA sequencing of the gene encoding a complement-inhibiting protein of Streptococcus pyogenes (streptococcal inhibitor of complement, Sic) was carried out on 49 strains of S. pyogenes serotype M1. Those strains were obtained from patients and asymptomatic carriers in Japan from 1969 to 1997 and had various pulsed-field gel electrophoresis (PFGE) patterns. Four identical polymorphic sites were found in the strains with the same PFGE pattern (Ia), but not in those giving the pattern IIa. The other identical sites were found in the strains with the PFGE pattern IIa, but not in those with the pattern Ia. These observations suggest that each of PFGE patterns was restricted to a set of variation in the sic gene. Springer-Verlag New York Inc., 2000 Murase Toshiyuki Department of Bacteriology and Pathology, Kanagawa Prefectural Public Health Laboratory, Yokohama 241-0815, Japan, JP aut Kameoka Yosuke Division of Genetic Resources, National Institute of Infectious Diseases, Tokyo 162-8640, Japan, JP aut Suzuki Rieko Department of Bacteriology and Pathology, Kanagawa Prefectural Public Health Laboratory, Yokohama 241-0815, Japan, JP aut Yamai Shiro Department of Bacteriology and Pathology, Kanagawa Prefectural Public Health Laboratory, Yokohama 241-0815, Japan, JP aut https://doi.org/10.1007/s002840010102 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002840010102 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Murase Toshiyuki Department of Bacteriology and Pathology, Kanagawa Prefectural Public Health Laboratory, Yokohama 241-0815, Japan, JP aut NATIONALLICENCE 700 1- Kameoka Yosuke Division of Genetic Resources, National Institute of Infectious Diseases, Tokyo 162-8640, Japan, JP aut NATIONALLICENCE 700 1- Suzuki Rieko Department of Bacteriology and Pathology, Kanagawa Prefectural Public Health Laboratory, Yokohama 241-0815, Japan, JP aut NATIONALLICENCE 700 1- Yamai Shiro Department of Bacteriology and Pathology, Kanagawa Prefectural Public Health Laboratory, Yokohama 241-0815, Japan, JP aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer