caa a22 4500 475748336 CHVBK 20180406123519.0 cr unu---uuuuu 170329e20000501xx s 000 0 eng 10.1023/A:1006681312249 doi (NATIONALLICENCE)springer-10.1023/A:1006681312249 Active Immunization of Humans with Dendritic Cells [Elektronische Daten] [Madhav Dhodapkar, Nina Bhardwaj] Dendritic cells (DCs) are potent antigen-presenting cells specialized to initiate T-cell immunity. The development of methods to generate large numbers of DCs has facilitated their application for immunotherapy. Recent studies have demonstrated the safety and immunogenicity of DCs in humans and have begun to outline the durability, kinetics, and nature of the elicited T-cell responses. However, DC-based immunotherapy remains a challenge and several parameters need to be examined to optimize immune responses, in order to maximize clinical efficacy against cancer and infectious diseases. Plenum Publishing Corporation, 2000 Dendritic cells nationallicence immunotherapy nationallicence tumor immunology nationallicence antiviral immunity nationallicence cytolytic T cells nationallicence Dhodapkar Madhav Laboratory of Cellular Physiology and Immunology, Rockefeller University, 10021, New York, New York aut Bhardwaj Nina Laboratory of Cellular Physiology and Immunology, Rockefeller University, 10021, New York, New York aut Journal of Clinical Immunology Kluwer Academic Publishers-Plenum Publishers 20/3(2000-05-01), 167-174 0271-9142 20:3<167 2000 20 10875 https://doi.org/10.1023/A:1006681312249 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1006681312249 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dhodapkar Madhav Laboratory of Cellular Physiology and Immunology, Rockefeller University, 10021, New York, New York aut NATIONALLICENCE 700 1- Bhardwaj Nina Laboratory of Cellular Physiology and Immunology, Rockefeller University, 10021, New York, New York aut NATIONALLICENCE 773 0- Journal of Clinical Immunology Kluwer Academic Publishers-Plenum Publishers 20/3(2000-05-01), 167-174 0271-9142 20:3<167 2000 20 10875 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer