caa a22 4500 475752015 CHVBK 20180406123526.0 cr unu---uuuuu 170329e20000101xx s 000 0 eng 10.1007/PL00010054 doi (NATIONALLICENCE)springer-10.1007/PL00010054 Spontaneous Regression of a Large Hepatocellular Carcinoma with Portal Vein Tumor Thrombi: Report of a Case [Elektronische Daten] [Takahiro Uenishi, Kazuhiro Hirohashi, Hiromu Tanaka, Takashi Ikebe, Hiroaki Kinoshita] A 65-year-old man with chronic hepatitis C showed a markedly elevated serum α-fetoprotein concentration. Computed tomography revealed a huge tumor occupying the entire right hepatic lobe. Three months later, the tumor regressed spontaneously from 12 cm to 7 cm in diameter without any medical treatment. A right hepatic lobectomy was performed 4 months after the initial diagnosis. The main tumor, located in the posterior inferior segment, was completely necrotic, and had a thick fibrous capsule. Many inflammatory cells had also infiltrated into the tumor. Only a small portion of a tumor thrombus in the portal vein and one of three intrahepatic metastases contained viable cancer cells. The tumor was found to be poorly differentiated hepatocellular carcinoma. Tumor regression may have been caused by a disturbance in hepatic circulation associated with the portal vein thrombus.: Springer-Verlag Tokyo, 2000 Key Words: spontaneous regression, hepatocellular carcinoma, right lobectomy nationallicence Uenishi Takahiro Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan, JP aut Hirohashi Kazuhiro Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan, JP aut Tanaka Hiromu Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan, JP aut Ikebe Takashi Second Department ofPathology, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan, JP aut Kinoshita Hiroaki Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan, JP aut https://doi.org/10.1007/PL00010054 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/PL00010054 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Uenishi Takahiro Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan, JP aut NATIONALLICENCE 700 1- Hirohashi Kazuhiro Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan, JP aut NATIONALLICENCE 700 1- Tanaka Hiromu Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan, JP aut NATIONALLICENCE 700 1- Ikebe Takashi Second Department ofPathology, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan, JP aut NATIONALLICENCE 700 1- Kinoshita Hiroaki Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan, JP aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer