caa a22 4500 475752511 CHVBK 20180406123528.0 cr unu---uuuuu 170329e20000901xx s 000 0 eng 10.1007/s005950070066 doi (NATIONALLICENCE)springer-10.1007/s005950070066 Solitary Brain Metastasis from Papillary Thyroid Carcinoma in a Patient with Depression: Report of a Case [Elektronische Daten] [Masayuki Maruyama, Shinya Kobayashi, Kiyoshi Shingu, Hisashi Nagashima, Kiyohide Nagamine, Yoshio Kasuga, Ryoji Kato, Fumiko Kameko, Jun Amano] Papillary carcinoma of the thyroid is a common thyroid malignancy with a relatively good prognosis. However, distant metastases may develop and become threatening, particularly to older patients, in a more aggressive manner. We report herein the clinical, radiological, and pathological findings of a patient with papillary thyroid carcinoma who had a solitary cerebral metastasis. The patient had been suffering from depression and had already undergone a hemithyroidectomy for primary thyroid carcinoma, and was known to have metastatic thryoid carcinoma of the lungs and bone. After the removal of the remnant thyroid gland prior to radioiodine (131I) therapy, he developed additional problems related to depression. Electroencephalography played an important role in identifying suspected brain metastasis and computed tomography demonstrated a space-occupying lesion in the left cerebral hemisphere. Consequently, an early removal of intracranial mass could be performed without any further life-threatening complications. Moreover, after removal of the brain mass the patient's depression improved immediately without the use of any antidepressants. This case report indicates the possibility that a patient's depression might be associated with brain metastasis from papillary thyroid carcinoma, and also suggests that an early diagnosis with the appropriate surgical management of a brain metastasis followed by radioiodine therapy could be valuable for achieving a prolonged disease-free period. Springer-Verlag, 2000 Key Words Thyroid carcinoma nationallicence Brain metastasis nationallicence Depression nationallicence Maruyama Masayuki Department of Surgery, aut Kobayashi Shinya Department of Surgery, aut Shingu Kiyoshi Department of Surgery, aut Nagashima Hisashi Department of Neurosurgery, and aut Nagamine Kiyohide Department of Psychiatry, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan, JP aut Kasuga Yoshio Department of Surgery, Matsushiro General Hospital, 183 Matsushiro, Nagano 381-1231, Japan, JP aut Kato Ryoji Department of Medical Science, Kagawa Prefectural College of Health Science, 281-1 Hara, Muremachi, Kagawa 761-0123, Japan, JP aut Kameko Fumiko Shinshu University School of Allied Medical Science, 3-1-1 Asahi, Matsumoto 390-8621, Japan, JP aut Amano Jun Department of Surgery, aut https://doi.org/10.1007/s005950070066 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s005950070066 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Maruyama Masayuki Department of Surgery aut NATIONALLICENCE 700 1- Kobayashi Shinya Department of Surgery aut NATIONALLICENCE 700 1- Shingu Kiyoshi Department of Surgery aut NATIONALLICENCE 700 1- Nagashima Hisashi Department of Neurosurgery, and aut NATIONALLICENCE 700 1- Nagamine Kiyohide Department of Psychiatry, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan, JP aut NATIONALLICENCE 700 1- Kasuga Yoshio Department of Surgery, Matsushiro General Hospital, 183 Matsushiro, Nagano 381-1231, Japan, JP aut NATIONALLICENCE 700 1- Kato Ryoji Department of Medical Science, Kagawa Prefectural College of Health Science, 281-1 Hara, Muremachi, Kagawa 761-0123, Japan, JP aut NATIONALLICENCE 700 1- Kameko Fumiko Shinshu University School of Allied Medical Science, 3-1-1 Asahi, Matsumoto 390-8621, Japan, JP aut NATIONALLICENCE 700 1- Amano Jun Department of Surgery aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer