caa a22 4500 475752791 CHVBK 20180406123529.0 cr unu---uuuuu 170329e20001201xx s 000 0 eng 10.1007/s005950070001 doi (NATIONALLICENCE)springer-10.1007/s005950070001 Tubular Carcinoma of the Breast: A Histologic Subtype Indicative of Breast-Conserving Therapy [Elektronische Daten] [Keisei Anan, Shoshu Mitsuyama, Keiyoshi Tamae, Kazuyoshi Nishihara, Toshimitsu Iwashita, Yuji Abe, Takaaki Ihara, Shousaku Nakahara, Fujio Katsumoto, Shigeaki Takeda, Satoshi Toyoshima] We reviewed the clinical and pathologic features of pure tubular carcinoma of the breast with particular emphasis on the reported risk factors associated with local recurrences and survival following breast-conserving therapy. Of 1653 cases of invasive breast cancer, 12 (0.7%) were identified as pure tubular carcinoma. Clinical/pathologic features of pure tubular carcinoma were compared with those of T1 invasive carcinoma of all other histologic types (T1 IC). Of the 12 patients with pure tubular carcinoma (median tumor diameter 1.4 cm; range 0.5-3.0 cm), a multicentric association was identified in one patient while a multifocal association was seen in two. One patient had nodal metastatic disease out of the ten who underwent axillary dissection. No lymphatic vessel invasion was identified in any tumors (P < 0.1 vs T1 IC). In addition, extensive intraductal spread was not present in any tumors (P < 0.05 vs T1 IC). This study shows that patients with pure tubular carcinoma are appropriate candidates for breast-conserving therapy based on the clinical/pathologic features. When a multifocal association is suspected preoperatively, either a wide local excision or a quadrantectomy which includes other lesions is thus recommended. Springer-Verlag, 2000 Key words Margin nationallicence Extensive intraductal carcinoma nationallicence Irradiation nationallicence Tubular carcinoma nationallicence Breast nationallicence Anan Keisei Departments of Surgery and aut Mitsuyama Shoshu Departments of Surgery and aut Tamae Keiyoshi Departments of Surgery and aut Nishihara Kazuyoshi Departments of Surgery and aut Iwashita Toshimitsu Departments of Surgery and aut Abe Yuji Departments of Surgery and aut Ihara Takaaki Departments of Surgery and aut Nakahara Shousaku Departments of Surgery and aut Katsumoto Fujio Departments of Surgery and aut Takeda Shigeaki Departments of Surgery and aut Toyoshima Satoshi Pathology, Kitakyushu Municipal Medical Center, Kokurakita-ku, 2-1-1 Bashaku, Kitakyushu 802-0077, Japan, JP aut https://doi.org/10.1007/s005950070001 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s005950070001 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Anan Keisei Departments of Surgery and aut NATIONALLICENCE 700 1- Mitsuyama Shoshu Departments of Surgery and aut NATIONALLICENCE 700 1- Tamae Keiyoshi Departments of Surgery and aut NATIONALLICENCE 700 1- Nishihara Kazuyoshi Departments of Surgery and aut NATIONALLICENCE 700 1- Iwashita Toshimitsu Departments of Surgery and aut NATIONALLICENCE 700 1- Abe Yuji Departments of Surgery and aut NATIONALLICENCE 700 1- Ihara Takaaki Departments of Surgery and aut NATIONALLICENCE 700 1- Nakahara Shousaku Departments of Surgery and aut NATIONALLICENCE 700 1- Katsumoto Fujio Departments of Surgery and aut NATIONALLICENCE 700 1- Takeda Shigeaki Departments of Surgery and aut NATIONALLICENCE 700 1- Toyoshima Satoshi Pathology, Kitakyushu Municipal Medical Center, Kokurakita-ku, 2-1-1 Bashaku, Kitakyushu 802-0077, Japan, JP aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer