caa a22 4500 47575302X CHVBK 20180406123529.0 cr unu---uuuuu 170329e20000301xx s 000 0 eng 10.1007/s005950050056 doi (NATIONALLICENCE)springer-10.1007/s005950050056 Crohn's disease of the esophagus: Report of a case [Elektronische Daten] [Manabu Ohta, Hiroyuki Konno, Kinji Kamiya, Daihachiro Suwa, Megumi Baba, Tatsuo Tanaka, Toshio Nakamura, Nobuhiko Nishino, Haruhiko Sugimura, Satoshi Nakamura] We report herein the case of a 27-year-old man with Crohn's disease of the esophagus. The patient presented with large ulcers in the esophagus for which treatment based on a diagnosis of reflux esophagitis was commenced. Although his symptoms were initially resolved, the ulcers did not improve and he was readmitted to hospital 3 months later for progressive heartburn. An esophagoscopy revealed large ulcers in the esophagus, and a colonoscopy revealed a longitudinal ulcer in the terminal ileum. Histological examination of specimens from the terminal ileum showed severe inflammation without granuloma formation, which led to a diagnosis of Crohn's disease. The oral administration of prednisolone and salazosulfapyridine controlled his symptoms and the esophageal ulcers were observed to be healing 2 weeks after this treatment was initiated. A review of the English literature revealed only 77 cases of this disease. Isolated esophageal lesions were reported in ten patients (13.0%), none of which were able to be diagnosed as Crohn's disease preoperatively. Ileocolic lesions developed after esophageal lesions in only five patients (6.5%) including ours. In the remaining 62 patients (80.5%), ileocolic lesions had existed synchronous with or prior to the esophageal lesions. This suggests that ileocolic lesions may often coexist in Crohn's patients with esophageal lesions, and that examination of the terminal ileum must be performed to confirm a diagnosis of Crohn's disease of the esophagus. Springer-Verlag, 2000 Crohn's disease nationallicence esophageal ulcer nationallicence prednisolone nationallicence salazosulfapyridine nationallicence Ohta Manabu Department of Surgery II, Hamamatsu University School of Medicine, 3600 Handa-cho, 431-3192, Hamamatsu, Japan aut Konno Hiroyuki Department of Surgery II, Hamamatsu University School of Medicine, 3600 Handa-cho, 431-3192, Hamamatsu, Japan aut Kamiya Kinji Department of Surgery II, Hamamatsu University School of Medicine, 3600 Handa-cho, 431-3192, Hamamatsu, Japan aut Suwa Daihachiro Department of Surgery II, Hamamatsu University School of Medicine, 3600 Handa-cho, 431-3192, Hamamatsu, Japan aut Baba Megumi Department of Surgery II, Hamamatsu University School of Medicine, 3600 Handa-cho, 431-3192, Hamamatsu, Japan aut Tanaka Tatsuo Department of Surgery II, Hamamatsu University School of Medicine, 3600 Handa-cho, 431-3192, Hamamatsu, Japan aut Nakamura Toshio Department of Surgery II, Hamamatsu University School of Medicine, 3600 Handa-cho, 431-3192, Hamamatsu, Japan aut Nishino Nobuhiko Department of Surgery II, Hamamatsu University School of Medicine, 3600 Handa-cho, 431-3192, Hamamatsu, Japan aut Sugimura Haruhiko First Department of Pathology, Hamamatsu University School of Medicine, 3600 Handa-cho, 431-3192, Hamamatsu, Japan aut Nakamura Satoshi Department of Surgery II, Hamamatsu University School of Medicine, 3600 Handa-cho, 431-3192, Hamamatsu, Japan aut Surgery Today Springer-Verlag 30/3(2000-03-01), 262-267 0941-1291 30:3<262 2000 30 595 https://doi.org/10.1007/s005950050056 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s005950050056 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ohta Manabu Department of Surgery II, Hamamatsu University School of Medicine, 3600 Handa-cho, 431-3192, Hamamatsu, Japan aut NATIONALLICENCE 700 1- Konno Hiroyuki Department of Surgery II, Hamamatsu University School of Medicine, 3600 Handa-cho, 431-3192, Hamamatsu, Japan aut NATIONALLICENCE 700 1- Kamiya Kinji Department of Surgery II, Hamamatsu University School of Medicine, 3600 Handa-cho, 431-3192, Hamamatsu, Japan aut NATIONALLICENCE 700 1- Suwa Daihachiro Department of Surgery II, Hamamatsu University School of Medicine, 3600 Handa-cho, 431-3192, Hamamatsu, Japan aut NATIONALLICENCE 700 1- Baba Megumi Department of Surgery II, Hamamatsu University School of Medicine, 3600 Handa-cho, 431-3192, Hamamatsu, Japan aut NATIONALLICENCE 700 1- Tanaka Tatsuo Department of Surgery II, Hamamatsu University School of Medicine, 3600 Handa-cho, 431-3192, Hamamatsu, Japan aut NATIONALLICENCE 700 1- Nakamura Toshio Department of Surgery II, Hamamatsu University School of Medicine, 3600 Handa-cho, 431-3192, Hamamatsu, Japan aut NATIONALLICENCE 700 1- Nishino Nobuhiko Department of Surgery II, Hamamatsu University School of Medicine, 3600 Handa-cho, 431-3192, Hamamatsu, Japan aut NATIONALLICENCE 700 1- Sugimura Haruhiko First Department of Pathology, Hamamatsu University School of Medicine, 3600 Handa-cho, 431-3192, Hamamatsu, Japan aut NATIONALLICENCE 700 1- Nakamura Satoshi Department of Surgery II, Hamamatsu University School of Medicine, 3600 Handa-cho, 431-3192, Hamamatsu, Japan aut NATIONALLICENCE 773 0- Surgery Today Springer-Verlag 30/3(2000-03-01), 262-267 0941-1291 30:3<262 2000 30 595 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer