caa a22 4500 475753097 CHVBK 20180406123530.0 cr unu---uuuuu 170329e20001001xx s 000 0 eng 10.1007/s005950070040 doi (NATIONALLICENCE)springer-10.1007/s005950070040 The clinical significance of lymph node metastases in patients undergoing surgery for hepatocellular carcinoma [Elektronische Daten] [Takahiro Uenishi, Kazuhiro Hirohashi, Taichi Shuto, Shoji Kubo, Hiromu Tanaka, Chikaharu Sakata, Takashi Ikebe, Hiroaki Kinoshita] The frequency of lymph node (LN) metastasis in patients undergoing surgery for hepatocellular carcinoma (HCC) has rarely been studied. We evaluated the clinicopathologic characteristics and outcomes of six patients with nodal metastases from HCC among a total of 504 patients who underwent hepatic resection for HCC in our department over a 16-year period. The nodal metastases were diagnosed preoperatively in two patients. The average diameter of the resected tumors was 7.8 cm and all were confirmed as poorly differentiated HCC. All of the six patients had intrahepatic metastatic nodules and five also had portal vein invasion. One patient underwent limited resection, and the other five underwent bisegmentectomy. All of the regional LNs were removed in one patient, while only enlarged LNs were removed in the other five. One patient died of postoperative liver failure and the others all died later of intrahepatic or nodal recurrence. Our findings suggest that the prognosis of patients with nodal metastasis from HCC is generally poor, even if hepatic resection with regional LN dissection is performed. Springer-Verlag, 2000 Hepatocellular carcinoma nationallicence Lymph node metastasis nationallicence Hepatic resection nationallicence Uenishi Takahiro Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut Hirohashi Kazuhiro Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut Shuto Taichi Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut Kubo Shoji Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut Tanaka Hiromu Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut Sakata Chikaharu Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut Ikebe Takashi Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut Kinoshita Hiroaki Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut Surgery Today Springer-Verlag 30/10(2000-10-01), 892-895 0941-1291 30:10<892 2000 30 595 https://doi.org/10.1007/s005950070040 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s005950070040 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Uenishi Takahiro Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut NATIONALLICENCE 700 1- Hirohashi Kazuhiro Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut NATIONALLICENCE 700 1- Shuto Taichi Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut NATIONALLICENCE 700 1- Kubo Shoji Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut NATIONALLICENCE 700 1- Tanaka Hiromu Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut NATIONALLICENCE 700 1- Sakata Chikaharu Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut NATIONALLICENCE 700 1- Ikebe Takashi Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut NATIONALLICENCE 700 1- Kinoshita Hiroaki Second Department of Surgery, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, 545-8585, Osaka, Japan aut NATIONALLICENCE 773 0- Surgery Today Springer-Verlag 30/10(2000-10-01), 892-895 0941-1291 30:10<892 2000 30 595 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer