caa a22 4500 475753135 CHVBK 20180406123530.0 cr unu---uuuuu 170329e20001001xx s 000 0 eng 10.1007/s005950070039 doi (NATIONALLICENCE)springer-10.1007/s005950070039 Key factors influencing bowel function after ileal W-pouch anal anastomosis: A spectral analysis of W-pouch motor activity [Elektronische Daten] [Tomoaki Maruta, Shinji Homma, Minoru Yagi, Jun Hasegawa, Kimitoshi Shimamura, Takeyasu Suda, Yasuo Sakai, Katsuyoshi Hatakeyama] Restorative proctocolectomy with ileal pouch anal anastomosis (IPAA) has become the standard surgical procedure for ulcerative colitis (UC). The purpose of this study was to determine which factors are important to achieve good anal continence after IPAA in terms of the motor activity and pressure-volume relationship. A total of 17 patients with UC who underwent IPAA were evaluated. The internal ileal pouch pressure was transanally measured with and without volume-loading of the pouch which induces the urge to evacuate. The maximum tolerable volume (MTV), first urge volume (FUV), and ileal pouch compliance were calculated and the internal ileal pouch pressure records were subjected to spectral analysis for intensive evaluation of the intraluminal pressure waves. The FUV, correlation of the compliance of the FUV with MTV, and the remaining volume up to the MTV (RVMTV) were analyzed. Compliance of the FUV was significantly correlated with the RVMTV (r=0.736,P < 0.01). The frequency of the phasic waves in the pouch decreased with length of follow up, reflecting improved function (r=−0.588,P < 0.05). The findings of this intensive analysis of manometric measurement indicate that the key factors in postoperative pouch function are RVMTV and the frequency of phasic waves in the W-pouch. Springer-Verlag, 2000 Ulcerative colitis nationallicence Ileal W-pouch nationallicence Spectral nationallicence analysis nationallicence Manovolumetry nationallicence Maruta Tomoaki First Department of Surgery, Niigata University Faculty of Medicine, 1-757 Asahimachi-dori, 951-8510, Niigata, Japan aut Homma Shinji Second Department of Physiology, Niigata University Faculty of Medicine, 1-757 Asahimachi-dori, 951-8510, Niigata, Japan aut Yagi Minoru Department of Pediatric Surgery, Niigata University Faculty of Medicine, 1-757 Asahimachi-dori, 951-8510, Niigata, Japan aut Hasegawa Jun First Department of Surgery, Niigata University Faculty of Medicine, 1-757 Asahimachi-dori, 951-8510, Niigata, Japan aut Shimamura Kimitoshi First Department of Surgery, Niigata University Faculty of Medicine, 1-757 Asahimachi-dori, 951-8510, Niigata, Japan aut Suda Takeyasu First Department of Surgery, Niigata University Faculty of Medicine, 1-757 Asahimachi-dori, 951-8510, Niigata, Japan aut Sakai Yasuo First Department of Surgery, Niigata University Faculty of Medicine, 1-757 Asahimachi-dori, 951-8510, Niigata, Japan aut Hatakeyama Katsuyoshi First Department of Surgery, Niigata University Faculty of Medicine, 1-757 Asahimachi-dori, 951-8510, Niigata, Japan aut Surgery Today Springer-Verlag 30/10(2000-10-01), 886-891 0941-1291 30:10<886 2000 30 595 https://doi.org/10.1007/s005950070039 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s005950070039 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Maruta Tomoaki First Department of Surgery, Niigata University Faculty of Medicine, 1-757 Asahimachi-dori, 951-8510, Niigata, Japan aut NATIONALLICENCE 700 1- Homma Shinji Second Department of Physiology, Niigata University Faculty of Medicine, 1-757 Asahimachi-dori, 951-8510, Niigata, Japan aut NATIONALLICENCE 700 1- Yagi Minoru Department of Pediatric Surgery, Niigata University Faculty of Medicine, 1-757 Asahimachi-dori, 951-8510, Niigata, Japan aut NATIONALLICENCE 700 1- Hasegawa Jun First Department of Surgery, Niigata University Faculty of Medicine, 1-757 Asahimachi-dori, 951-8510, Niigata, Japan aut NATIONALLICENCE 700 1- Shimamura Kimitoshi First Department of Surgery, Niigata University Faculty of Medicine, 1-757 Asahimachi-dori, 951-8510, Niigata, Japan aut NATIONALLICENCE 700 1- Suda Takeyasu First Department of Surgery, Niigata University Faculty of Medicine, 1-757 Asahimachi-dori, 951-8510, Niigata, Japan aut NATIONALLICENCE 700 1- Sakai Yasuo First Department of Surgery, Niigata University Faculty of Medicine, 1-757 Asahimachi-dori, 951-8510, Niigata, Japan aut NATIONALLICENCE 700 1- Hatakeyama Katsuyoshi First Department of Surgery, Niigata University Faculty of Medicine, 1-757 Asahimachi-dori, 951-8510, Niigata, Japan aut NATIONALLICENCE 773 0- Surgery Today Springer-Verlag 30/10(2000-10-01), 886-891 0941-1291 30:10<886 2000 30 595 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer