caa a22 4500 475753240 CHVBK 20180406123530.0 cr unu---uuuuu 170329e20001001xx s 000 0 eng 10.1007/s005950070045 doi (NATIONALLICENCE)springer-10.1007/s005950070045 Completion pneumonectomy of the residual left lung to treat lung cancer in a patient with hemophilia a: Report of a case [Elektronische Daten] [Yasushi Nomoto, Hideki Kimura, Naomichi Iwai, Teruaki Mizobuchi, Sana Yokoi, Kyoya Kumagai] Hemophilia A is a sex-linked recessive hereditary disease that is relatively rare and the number of patients with this disorder who undergo major surgery is limited. Although replenishing coagulation factors can allow hemophiliac patients to undergo similar surgery to that performed for patients without hemophilia, there have been few reports on major surgery and none on the resection of lung cancer in patients with hemophilia A. We recently performed completion pneumonectomy of the left lung in a 70-year-old man with hemophilia A, for squamous cell carcinoma in the residual left lung. The administration of a recombinant DNA coagulation factor VIII preparation allowed this operation to be successfully carried out. This case serves to demonstrate that the recombinant DNA coagulation factor VIII preparation described may enable us to safely perform major surgery on hemophiliac patients, since there is no risk of viral infection or any other adverse effects, such as deterioration of immunocompetence or hemolysis, which are occasionally encountered with human plasma-derived preparations. Springer-Verlag, 2000 Lung cancer nationallicence Operation nationallicence Hemophilia nationallicence Recombinant DNA nationallicence Coagulation factor VIII nationallicence Nomoto Yasushi Division of Thoracic Diseases, Chiba Cancer Center, 666-2 Nitona-cho, Chuo-ku, 260-8717, Chiba, Japan aut Kimura Hideki Division of Thoracic Diseases, Chiba Cancer Center, 666-2 Nitona-cho, Chuo-ku, 260-8717, Chiba, Japan aut Iwai Naomichi Division of Thoracic Diseases, Chiba Cancer Center, 666-2 Nitona-cho, Chuo-ku, 260-8717, Chiba, Japan aut Mizobuchi Teruaki Division of Thoracic Diseases, Chiba Cancer Center, 666-2 Nitona-cho, Chuo-ku, 260-8717, Chiba, Japan aut Yokoi Sana Division of Thoracic Diseases, Chiba Cancer Center, 666-2 Nitona-cho, Chuo-ku, 260-8717, Chiba, Japan aut Kumagai Kyoya Division of Hematology and Chemotherapy, Chiba Cancer Center, 666-2 Nitona-cho, Chuo-ku, 260-8717, Chiba, Japan aut Surgery Today Springer-Verlag 30/10(2000-10-01), 917-920 0941-1291 30:10<917 2000 30 595 https://doi.org/10.1007/s005950070045 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s005950070045 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nomoto Yasushi Division of Thoracic Diseases, Chiba Cancer Center, 666-2 Nitona-cho, Chuo-ku, 260-8717, Chiba, Japan aut NATIONALLICENCE 700 1- Kimura Hideki Division of Thoracic Diseases, Chiba Cancer Center, 666-2 Nitona-cho, Chuo-ku, 260-8717, Chiba, Japan aut NATIONALLICENCE 700 1- Iwai Naomichi Division of Thoracic Diseases, Chiba Cancer Center, 666-2 Nitona-cho, Chuo-ku, 260-8717, Chiba, Japan aut NATIONALLICENCE 700 1- Mizobuchi Teruaki Division of Thoracic Diseases, Chiba Cancer Center, 666-2 Nitona-cho, Chuo-ku, 260-8717, Chiba, Japan aut NATIONALLICENCE 700 1- Yokoi Sana Division of Thoracic Diseases, Chiba Cancer Center, 666-2 Nitona-cho, Chuo-ku, 260-8717, Chiba, Japan aut NATIONALLICENCE 700 1- Kumagai Kyoya Division of Hematology and Chemotherapy, Chiba Cancer Center, 666-2 Nitona-cho, Chuo-ku, 260-8717, Chiba, Japan aut NATIONALLICENCE 773 0- Surgery Today Springer-Verlag 30/10(2000-10-01), 917-920 0941-1291 30:10<917 2000 30 595 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer