caa a22 4500 475753283 CHVBK 20180406123530.0 cr unu---uuuuu 170329e20000301xx s 000 0 eng 10.1007/s005950050596 doi (NATIONALLICENCE)springer-10.1007/s005950050596 Recovery of Parathyroid Function After Total Thyroidectomy [Elektronische Daten] [Minoru Kihara, Hiroyasu Yokomise, Akira Miyauchi, Kenichi Matsusaka] To prevent postoperative hypoparathyroidism following total thyroidectomy, the parathyroid glands are preserved in situ and/or resected or devascularized parathyroid glands are autotransplanted. We conducted a retrospective investigation utilizing biochemical and specific endocrine assessments to evaluate the difference in recovery of parathyroid function between the two operative methods. A total of 92 patients underwent total thyroidectomy at our hospital during the period between 1990 and 1997. These patients were divided into a preservation group (n = 83), with one or more preserved glands in situ, and an autotransplantation group (n = 9), with only transplanted glands. The level of intact parathyroid hormone (PTH) was completely restored by 1 year postoperatively in 83% (69/83) of the preservation group patients. In the remaining 14 patients (17%), the intact PTH had fallen below detectable levels on postoperative day (POD) 1, then subsequently recovered to 70% of the preoperative levels. Comparatively, in the autotransplantation group, the mean level of intact PTH recovered to only 43% of the preoperative levels. The results of this study suggest that parathyroid glands should be preserved in situ whenever possible, and that when intact PTH levels fall below detectable limits on POD 1, they may never recover to the preoperative levels in those patients.: Springer-Verlag Tokyo, 2000 Key Words: parathyroid gland, preservation, autotransplantation, total thyroidectomy, intact parathyroid hormone nationallicence Kihara Minoru Second Department of Surgery, Kagawa Medical University, 1750-1 Miki-cho, Kita-gun, Kagawa 761-0793, Japan, JP aut Yokomise Hiroyasu Second Department of Surgery, Kagawa Medical University, 1750-1 Miki-cho, Kita-gun, Kagawa 761-0793, Japan, JP aut Miyauchi Akira Kuma Hospital, 8-2-35 Shimoyamate-dori, Chuo-ku, Kobe 650-0011, Japan, JP aut Matsusaka Kenichi Higashiura Heisei Hospital, 1867 Kuruma, Higashiura-cho, Tsuna-gun, Hyogo 656-2351, Japan, JP aut https://doi.org/10.1007/s005950050596 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s005950050596 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kihara Minoru Second Department of Surgery, Kagawa Medical University, 1750-1 Miki-cho, Kita-gun, Kagawa 761-0793, Japan, JP aut NATIONALLICENCE 700 1- Yokomise Hiroyasu Second Department of Surgery, Kagawa Medical University, 1750-1 Miki-cho, Kita-gun, Kagawa 761-0793, Japan, JP aut NATIONALLICENCE 700 1- Miyauchi Akira Kuma Hospital, 8-2-35 Shimoyamate-dori, Chuo-ku, Kobe 650-0011, Japan, JP aut NATIONALLICENCE 700 1- Matsusaka Kenichi Higashiura Heisei Hospital, 1867 Kuruma, Higashiura-cho, Tsuna-gun, Hyogo 656-2351, Japan, JP aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer