caa a22 4500 475753291 CHVBK 20180406123530.0 cr unu---uuuuu 170329e20000301xx s 000 0 eng 10.1007/s005950050605 doi (NATIONALLICENCE)springer-10.1007/s005950050605 Pancreatic Lesions in von Hippel-Lindau Syndrome: The Coexistence of Metastatic Tumors from Renal Cell Carcinoma and Multiple Cysts [Elektronische Daten] [Masafumi Kogire, Ryo Hosotani, Masato Kondo, Kyo Itoh, Ryuichiro Doi, Toshiro Terachi, Masayuki Imamura] Multiple cysts and benign cystadenomas of the pancreas have been documented occasionally in von Hippel-Lindau syndrome (HLS); however, the malignant involvement of the pancreas in HLS is very rare. We report a case of HLS in which metastatic tumors from renal cell carcinoma (RCC) coexisted with multiple cysts in the pancreas. A 22-year-old woman with a history of HLS had undergone a partial resection of the left kidney for RCC 3 years earlier, at which time a solid mass in the pancreatic tail and multiple pancreatic cysts were also incidentally detected by computed tomography. Over the following 3 years, the mass enlarged slightly, thus raising suspicions that it might be a primary neoplasm of the pancreas. She was referred to the Department of Surgery and Surgical Basic Science to undergo surgery. In addition to the tumor in the pancreatic tail, however, further tumors in the pancreatic head were also disclosed by preoperative celiac arteriography and intraoperative palpation and ultrasonography. A distal pancreatectomy was performed, because the enucleation of all the tumors in the pancreatic head was technically impossible and because the patient declined a total pancreatectomy. A histologic examination of the mass in the pancreatic tail revealed metastatic RCC. This case emphasizes that metastatic disease should be included in the differential diagnosis when evaluating the pancreas in a patient with HLS.: Springer-Verlag Tokyo, 2000 Key Words: pancreas, metastasis, cyst, renal cell carcinoma, von Hippel-Lindau syndrome nationallicence Kogire Masafumi Department of Surgery and Surgical Basic Science, Kyoto University,54 Shogoin Kawara-cho, Sakyo-ku, Kyoto 606, Japan, JP aut Hosotani Ryo Department of Surgery and Surgical Basic Science, Kyoto University,54 Shogoin Kawara-cho, Sakyo-ku, Kyoto 606, Japan, JP aut Kondo Masato Department of Surgery and Surgical Basic Science, Kyoto University,54 Shogoin Kawara-cho, Sakyo-ku, Kyoto 606, Japan, JP aut Itoh Kyo Department of Nuclear Medicine, Kyoto University,54 Shogoin Kawara-cho, Sakyo-ku, Kyoto 606, Japan, JP aut Doi Ryuichiro Department of Surgery and Surgical Basic Science, Kyoto University,54 Shogoin Kawara-cho, Sakyo-ku, Kyoto 606, Japan, JP aut Terachi Toshiro Department of Urology, Graduate School of Medicine, Kyoto University,54 Shogoin Kawara-cho, Sakyo-ku, Kyoto 606, Japan, JP aut Imamura Masayuki Department of Surgery and Surgical Basic Science, Kyoto University,54 Shogoin Kawara-cho, Sakyo-ku, Kyoto 606, Japan, JP aut https://doi.org/10.1007/s005950050605 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s005950050605 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kogire Masafumi Department of Surgery and Surgical Basic Science, Kyoto University,54 Shogoin Kawara-cho, Sakyo-ku, Kyoto 606, Japan, JP aut NATIONALLICENCE 700 1- Hosotani Ryo Department of Surgery and Surgical Basic Science, Kyoto University,54 Shogoin Kawara-cho, Sakyo-ku, Kyoto 606, Japan, JP aut NATIONALLICENCE 700 1- Kondo Masato Department of Surgery and Surgical Basic Science, Kyoto University,54 Shogoin Kawara-cho, Sakyo-ku, Kyoto 606, Japan, JP aut NATIONALLICENCE 700 1- Itoh Kyo Department of Nuclear Medicine, Kyoto University,54 Shogoin Kawara-cho, Sakyo-ku, Kyoto 606, Japan, JP aut NATIONALLICENCE 700 1- Doi Ryuichiro Department of Surgery and Surgical Basic Science, Kyoto University,54 Shogoin Kawara-cho, Sakyo-ku, Kyoto 606, Japan, JP aut NATIONALLICENCE 700 1- Terachi Toshiro Department of Urology, Graduate School of Medicine, Kyoto University,54 Shogoin Kawara-cho, Sakyo-ku, Kyoto 606, Japan, JP aut NATIONALLICENCE 700 1- Imamura Masayuki Department of Surgery and Surgical Basic Science, Kyoto University,54 Shogoin Kawara-cho, Sakyo-ku, Kyoto 606, Japan, JP aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer