caa a22 4500 475753313 CHVBK 20180406123530.0 cr unu---uuuuu 170329e20000301xx s 000 0 eng 10.1007/s005950050601 doi (NATIONALLICENCE)springer-10.1007/s005950050601 Composite Tumor with Papillary Adenocarcinoma and Squamous Cell Carcinoma of the Esophagus: Report of a Case [Elektronische Daten] [Satoru Nakagawa, Tadashi Nishimaki, Tatsuo Kanda, Tsutomu Suzuki, Katsuyoshi Hatakeyama] Papillary adenocarcinoma is extremely rare in the squamous epithelium-lined esophagus. The histopathologic and immunohistochemical characteristics were examined in a composite tumor showing distinct papillary adenocarcinoma and squamous cell carcinoma of the esophagus resected from a 66-year-old man. The esophageal tumor consisted both grossly and histologically of two distinct components: an ulcerative part showing a squamous cell carcinoma, and a polypoid part corresponding to a papillary adenocarcinoma. In addition, the in situ squamous cell carcinoma was contiguous with the esophageal tumor. Mucin secretion was found only in the papillary adenocarcinoma component. Immunohistochemically, tumor cells of the papillary adenocarci-noma component were positive for carcinoembryonic antigen, secretory component, and lactoferrin. These staining patterns were similar to those of the normal esophageal gland proper. These histologic, mucin-histochemical, and immunohistochemical findings suggest that the papillary adenocarcinoma originated from the submucosal esophageal gland and the squamous cell carcinoma from the squamous epithelium lining the esophagus.: Springer-Verlag Tokyo, 2000 Key Words: papillary adenocarcinoma, esophageal neoplasm nationallicence Nakagawa Satoru First Department of Surgery, Niigata University School of Medicine, Asahimachi-dori 1-757, Niigata 951-8122, Japan, JP aut Nishimaki Tadashi First Department of Surgery, Niigata University School of Medicine, Asahimachi-dori 1-757, Niigata 951-8122, Japan, JP aut Kanda Tatsuo First Department of Surgery, Niigata University School of Medicine, Asahimachi-dori 1-757, Niigata 951-8122, Japan, JP aut Suzuki Tsutomu First Department of Surgery, Niigata University School of Medicine, Asahimachi-dori 1-757, Niigata 951-8122, Japan, JP aut Hatakeyama Katsuyoshi First Department of Surgery, Niigata University School of Medicine, Asahimachi-dori 1-757, Niigata 951-8122, Japan, JP aut https://doi.org/10.1007/s005950050601 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s005950050601 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nakagawa Satoru First Department of Surgery, Niigata University School of Medicine, Asahimachi-dori 1-757, Niigata 951-8122, Japan, JP aut NATIONALLICENCE 700 1- Nishimaki Tadashi First Department of Surgery, Niigata University School of Medicine, Asahimachi-dori 1-757, Niigata 951-8122, Japan, JP aut NATIONALLICENCE 700 1- Kanda Tatsuo First Department of Surgery, Niigata University School of Medicine, Asahimachi-dori 1-757, Niigata 951-8122, Japan, JP aut NATIONALLICENCE 700 1- Suzuki Tsutomu First Department of Surgery, Niigata University School of Medicine, Asahimachi-dori 1-757, Niigata 951-8122, Japan, JP aut NATIONALLICENCE 700 1- Hatakeyama Katsuyoshi First Department of Surgery, Niigata University School of Medicine, Asahimachi-dori 1-757, Niigata 951-8122, Japan, JP aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer