caa a22 4500 475753356 CHVBK 20180406123530.0 cr unu---uuuuu 170329e20000301xx s 000 0 eng 10.1007/s005950050592 doi (NATIONALLICENCE)springer-10.1007/s005950050592 Early Diagnosis of Postoperative Infection: Assessment of Whole Blood Chemiluminescence [Elektronische Daten] [Minoru Fujisawa, Kuniaki Kojima, Tomoe Beppu, Shunji Futagawa, Kyoko Kuwahara, Keiichi Hiramatsu] Whole blood chemiluminescence (CL), which allows for the evaluation of both the oxygen radical release by phagocytes and the serum opsonin activity using very small amounts of blood, is considered to be a useful means of assessing the host defense against infection. We measured the whole blood chemiluminescence in 59 patients before and after open surgery (surgery by a laparotomy) for gastrointestinal disease. Early postoperative infection was detected in 12 (20.3%) of the 59 patients. These 12 patients all had significantly higher white blood cell counts compared with the noninfected patients on the third and subsequent days after surgery (P < 0.01). The peak CL in the early postoperative infected group was also significantly higher than that in the noninfected group on the day of surgery (P < 0.0001), 1 day after surgery (P <≧0.0001), and 3 days after surgery (P < 0.01). Whole blood CL may therefore be a useful modality for the early detection of postoperative infection in the future.: Springer-Verlag Tokyo, 2000 Key Words: whole blood chemiluminescence, oxygen radical release, early postoperative infection nationallicence Fujisawa Minoru Second Department of Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan, JP aut Kojima Kuniaki Second Department of Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan, JP aut Beppu Tomoe Second Department of Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan, JP aut Futagawa Shunji Second Department of Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan, JP aut Kuwahara Kyoko Department of Bacteriology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan, JP aut Hiramatsu Keiichi Department of Bacteriology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan, JP aut https://doi.org/10.1007/s005950050592 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s005950050592 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Fujisawa Minoru Second Department of Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan, JP aut NATIONALLICENCE 700 1- Kojima Kuniaki Second Department of Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan, JP aut NATIONALLICENCE 700 1- Beppu Tomoe Second Department of Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan, JP aut NATIONALLICENCE 700 1- Futagawa Shunji Second Department of Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan, JP aut NATIONALLICENCE 700 1- Kuwahara Kyoko Department of Bacteriology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan, JP aut NATIONALLICENCE 700 1- Hiramatsu Keiichi Department of Bacteriology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan, JP aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer