caa a22 4500 475753844 CHVBK 20180406123532.0 cr unu---uuuuu 170329e20000501xx s 000 0 eng 10.1007/s005950050613 doi (NATIONALLICENCE)springer-10.1007/s005950050613 The effectiveness of preoperative intraluminal brachytherapy in preventing wall penetration and nodal involvement of rectal carcinomas [Elektronische Daten] [Hidenori Yanagi, Masato Kusunoki, Takehira Yamamura] A retrosp4ective review was conducted of 115 patients with middle or lower rectal carcinoma, without distant metastasis, who were consecutively treated with preoperative intraluminal brachytherapy and radical surgery (IBT group). Another 115 rectal carcinoma patients treated with surgery alone were reviewed as a control (NIBT group). We investigated whether conventional pathologic stagings were correlated with prognosis. All tumors were diagnosed by the TNM classification. According to the distribution of pathologic staging in the resected specimens, the prevalence of totally ablated tumors (stage T0) in the IBT group was significantly higher than that in the NIBT group, but there were no significant differences in the distribution of other T stages between the two groups. Good local control was achieved for the stage-T3 tumors in the IBT group, similarly to the T ≦ 2 tumors in both groups. In the IBT group, the survival period of the patients with stage-T4 tumors even after radiotherapy was significantly shorter than that of those with T3 tumors (P=0.042), while those with N≦2-stage tumors had significantly longer survival periods than those with N3-stage tumors (P=0.047). These findings demonstrate the usefulness of analyzing clinicopathologic parameters to predict local control and the prolongation of survival. Determing these factors will also help to identify high-risk patients likely to require more effective adjuvant chemotherapy. Springer-Verlag, 2000 rectal carcinoma nationallicence radiotherapy nationallicence intraluminal brachytherapy nationallicence pathology nationallicence Yanagi Hidenori Second Departmentt of Surgery, Hyogo College of Medicine, 1-1 Mukogawa-cho, 663, Nishinomiya, Hyogo, Japan aut Kusunoki Masato Second Departmentt of Surgery, Hyogo College of Medicine, 1-1 Mukogawa-cho, 663, Nishinomiya, Hyogo, Japan aut Yamamura Takehira Second Departmentt of Surgery, Hyogo College of Medicine, 1-1 Mukogawa-cho, 663, Nishinomiya, Hyogo, Japan aut Surgery Today Springer-Verlag 30/5(2000-05-01), 410-415 0941-1291 30:5<410 2000 30 595 https://doi.org/10.1007/s005950050613 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s005950050613 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yanagi Hidenori Second Departmentt of Surgery, Hyogo College of Medicine, 1-1 Mukogawa-cho, 663, Nishinomiya, Hyogo, Japan aut NATIONALLICENCE 700 1- Kusunoki Masato Second Departmentt of Surgery, Hyogo College of Medicine, 1-1 Mukogawa-cho, 663, Nishinomiya, Hyogo, Japan aut NATIONALLICENCE 700 1- Yamamura Takehira Second Departmentt of Surgery, Hyogo College of Medicine, 1-1 Mukogawa-cho, 663, Nishinomiya, Hyogo, Japan aut NATIONALLICENCE 773 0- Surgery Today Springer-Verlag 30/5(2000-05-01), 410-415 0941-1291 30:5<410 2000 30 595 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer