caa a22 4500 475754921 CHVBK 20180406123535.0 cr unu---uuuuu 170329e20000601xx s 000 0 eng 10.1007/s002470000244 doi (NATIONALLICENCE)springer-10.1007/s002470000244 Hoffer F. A. Department of Diagnostic Imaging, St. Jude Children's Research Hospital, 332 North Lauderdale St., Memphis, TN 38105-2794, USA e-mail: fred.hoffer@stjude.org Tel.: + 19 01-4 95 25 07 Fax: + 19 01-4 95 43 98, US aut Liver biopsy methods for pediatric oncology patients [Elektronische Daten] [F. A. Hoffer] Background. Liver biopsy is a high-risk procedure in oncology patients, and optimal methods for children have not been established.¶Objective. To assess the effectiveness and safety of two methods of performing liver biopsy in pediatric oncology patients.¶Materials and methods. Between May 1997 and July 1999, 51 liver biopsies (22 percutaneous and 29 transjugular) were performed. The 22 percutaneous biopsies (13 focal hepatic lesions and 9 general liver biopsies) were performed under sonographic guidance; 21 used a spring-loaded needle (usually 18 G). In 21 patients, a coaxial sheath was used to inject a slurry of microfibrillar collagen into the needle track. The 29 transjugular general liver biopsies were performed with a 19-G spring-loaded needle, under sonographic and fluoroscopic guidance. The transjugular technique was used for children with thrombocytopenia, coagulopathy, ascites, or recent bone-marrow transplantation.¶Results. All biopsies yielded sufficient tissue for diagnostic studies. Bleeding occurred after 3 of 21 percutaneous biopsies, despite coaxial track embolization. No bleeding or other major complication occurred after transjugular biopsy.¶Conclusion. Coaxial percutaneous biopsy with track embolization was effective, but was not complication-free; it should be reserved for focal lesions or for patients at low risk of bleeding. Transjugular liver biopsy is safe and effective for use in high-risk pediatric oncology patients. Springer-Verlag Berlin Heidelberg, 2000 https://doi.org/10.1007/s002470000244 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002470000244 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Hoffer F. A. Department of Diagnostic Imaging, St. Jude Children's Research Hospital, 332 North Lauderdale St., Memphis, TN 38105-2794, USA e-mail: fred.hoffer@stjude.org Tel.: + 19 01-4 95 25 07 Fax: + 19 01-4 95 43 98, US aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer