caa a22 4500 475756010 CHVBK 20180406123538.0 cr unu---uuuuu 170329e20000701xx s 000 0 eng 10.1007/s002470000270 doi (NATIONALLICENCE)springer-10.1007/s002470000270 Combined static-dynamic MR urography for the simultaneous evaluation of morphology and function in urinary tract obstruction [Elektronische Daten] I. Evaluation of the normal status in an animal model [W. K. Rohrschneider, Johannes Hoffend, Kristianna Becker, John H. Clorius, Kassa Darge, Hendrik Kooijman, Jochen Tröger] Objective. A new approach, combined static-dynamic MR urography is evaluated to determine its potential utility for the functional-morphological diagnosis of paediatric urinary tract obstruction. In this initial investigation we sought to evaluate the procedure by imaging the urinary tract of piglets. Materials and methods. Twenty-nine healthy piglets were studied with MR urography (MRU), 99 mTc-MAG3 diuretic renal scintigraphy (DRS), ultrasound (US) and excretory urography (EU). The functional and morphological findings were compared. For MRU we combined a respiration-triggered 3D-IR-TSE sequence and a dynamic 2D-FFE sequence after Gd-DTPA injection. Results. MRU depicted the complete urinary tract with superior image quality compared to EU. Calculation of time-intensity curves from the dynamic sequence permitted determination of single kidney function from parenchymal ROIs and urinary excretion using the whole kidney ROI. MRU and DRS showed significant agreement in the assessment of both single kidney function and urinary excretion. Disturbances of urinary drainage were generally caused by an overfilled bladder. Conclusions. Combined static-dynamic MRU is well suited for the depiction of the complete urinary tract and for the determination of individual kidney function and urinary excretion in the piglet. Springer-Verlag Berlin Heidelberg, 2000 Rohrschneider W. K. Paediatric Radiology, University of Heidelberg, Im Neuenheimer Feld 153, 69120 Heidelberg, Germany, DE aut Hoffend Johannes Paediatric Radiology, University of Heidelberg, Im Neuenheimer Feld 153, 69120 Heidelberg, Germany, DE aut Becker Kristianna Paediatric Radiology, University of Heidelberg, Im Neuenheimer Feld 153, 69120 Heidelberg, Germany, DE aut Clorius John H. Paediatric Radiology, University of Heidelberg, Im Neuenheimer Feld 153, 69120 Heidelberg, Germany, DE aut Darge Kassa Paediatric Radiology, University of Heidelberg, Im Neuenheimer Feld 153, 69120 Heidelberg, Germany, DE aut Kooijman Hendrik Paediatric Radiology, University of Heidelberg, Im Neuenheimer Feld 153, 69120 Heidelberg, Germany, DE aut Tröger Jochen Paediatric Radiology, University of Heidelberg, Im Neuenheimer Feld 153, 69120 Heidelberg, Germany, DE aut https://doi.org/10.1007/s002470000270 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002470000270 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Rohrschneider W. K. Paediatric Radiology, University of Heidelberg, Im Neuenheimer Feld 153, 69120 Heidelberg, Germany, DE aut NATIONALLICENCE 700 1- Hoffend Johannes Paediatric Radiology, University of Heidelberg, Im Neuenheimer Feld 153, 69120 Heidelberg, Germany, DE aut NATIONALLICENCE 700 1- Becker Kristianna Paediatric Radiology, University of Heidelberg, Im Neuenheimer Feld 153, 69120 Heidelberg, Germany, DE aut NATIONALLICENCE 700 1- Clorius John H. Paediatric Radiology, University of Heidelberg, Im Neuenheimer Feld 153, 69120 Heidelberg, Germany, DE aut NATIONALLICENCE 700 1- Darge Kassa Paediatric Radiology, University of Heidelberg, Im Neuenheimer Feld 153, 69120 Heidelberg, Germany, DE aut NATIONALLICENCE 700 1- Kooijman Hendrik Paediatric Radiology, University of Heidelberg, Im Neuenheimer Feld 153, 69120 Heidelberg, Germany, DE aut NATIONALLICENCE 700 1- Tröger Jochen Paediatric Radiology, University of Heidelberg, Im Neuenheimer Feld 153, 69120 Heidelberg, Germany, DE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence SWISSBIB 475756010 BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer