caa a22 4500 475758536 CHVBK 20180406123543.0 cr unu---uuuuu 170329e20000101xx s 000 0 eng 10.1007/BF02499072 doi (NATIONALLICENCE)springer-10.1007/BF02499072 Synthesis of 11-hydroxydrim-8(9)-en-7-one and 11,12-dihydroxydrim-8(9)-en-7-one from drim-8(9)-en-7-one [Elektronische Daten] [P. Vlad, D. Popa, E. Gorincioi, M. Coltsa, G. Mironov] A synthetic route to 11-hydroxydrim-8(9)-en-7-one and 11,12-hydroxydrim-8(9)-en-7-one, valuable key intermediates for the preparation of naturally occurring biologically active drimanic sesquiterpenoids, starting from easily available drim-8(9)-en-7-one was developed. 11-Hydroxydrim-8(9)-en-7-one was obtained by peracidic oxidation of the enol acetate of drim-8(9)-en-7-one. 11,12-Dihydroxydrim-8(9)-en-7-one was synthesized from drim-8(9)-en-7-one by two routes, namely, by a five-step procedurevia 11-hydroxydrim-8(9)-en-7-one and by bromination of drim-8(9)-en-7-one with NBS to give 11,12-dibromodrim-8(9)-en-7-one followed by its acetoxylation and deacetylation. Kluwer Academic/Plenum Publishers, 2000 drimanic sesquiterpenoids nationallicence synthesis nationallicence drim-8(9)-en-7-one nationallicence 11-hydroxydrim-8(9)-en-7-one nationallicence 11,12-dihydroxydrim-8(9)-en-7-one nationallicence Vlad P. Institute of Chemistry, Academy of Sciences of Republic of Moldova, 3 str. Academiei, MD-2028, Chişinâu, Republic of Moldova aut Popa D. Institute of Chemistry, Academy of Sciences of Republic of Moldova, 3 str. Academiei, MD-2028, Chişinâu, Republic of Moldova aut Gorincioi E. Institute of Chemistry, Academy of Sciences of Republic of Moldova, 3 str. Academiei, MD-2028, Chişinâu, Republic of Moldova aut Coltsa M. Institute of Chemistry, Academy of Sciences of Republic of Moldova, 3 str. Academiei, MD-2028, Chişinâu, Republic of Moldova aut Mironov G. Institute of Chemistry, Academy of Sciences of Republic of Moldova, 3 str. Academiei, MD-2028, Chişinâu, Republic of Moldova aut Russian Chemical Bulletin Kluwer Academic Publishers-Plenum Publishers 49/1(2000-01-01), 98-101 1066-5285 49:1<98 2000 49 11172 https://doi.org/10.1007/BF02499072 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02499072 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Vlad P. Institute of Chemistry, Academy of Sciences of Republic of Moldova, 3 str. Academiei, MD-2028, Chişinâu, Republic of Moldova aut NATIONALLICENCE 700 1- Popa D. Institute of Chemistry, Academy of Sciences of Republic of Moldova, 3 str. Academiei, MD-2028, Chişinâu, Republic of Moldova aut NATIONALLICENCE 700 1- Gorincioi E. Institute of Chemistry, Academy of Sciences of Republic of Moldova, 3 str. Academiei, MD-2028, Chişinâu, Republic of Moldova aut NATIONALLICENCE 700 1- Coltsa M. Institute of Chemistry, Academy of Sciences of Republic of Moldova, 3 str. Academiei, MD-2028, Chişinâu, Republic of Moldova aut NATIONALLICENCE 700 1- Mironov G. Institute of Chemistry, Academy of Sciences of Republic of Moldova, 3 str. Academiei, MD-2028, Chişinâu, Republic of Moldova aut NATIONALLICENCE 773 0- Russian Chemical Bulletin Kluwer Academic Publishers-Plenum Publishers 49/1(2000-01-01), 98-101 1066-5285 49:1<98 2000 49 11172 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer