caa a22 4500 475763491 CHVBK 20180406123558.0 cr unu---uuuuu 170329e20000601xx s 000 0 eng 10.1007/s003960050554 doi (NATIONALLICENCE)springer-10.1007/s003960050554 Surfactant-modified zeolites as a drug carrier and the release of chloroquin [Elektronische Daten] [K. Hayakawa, Y. Mouri, T. Maeda, I. Satake, M. Sato]  The adsolubilization of chloroquin (CQ) by complexes of zeolites with hexadecyl-, tetradecyl-, and dodecyltrimethylammonium bromides was determined by spectrophotometry. The zeolites used were P-type zeolite (ZP) with a sodium counterion and X-type zeolites with sodium (NX) or calcium (CX) counterions. ZP adsorbed CQ without surfactant, but the ZP surfactant complexes enhanced the adsorption of CQ. Without surfactant, NX and CX did not adsorb CQ, but the surfactant complexes induced the adsorption of CQ. Since the surfactants and CQ were cationic under the experimental conditions, the enhanced CQ incorporation was ascribed to the adsolubilization of CQ by the zeolite/surfactant complexes. The NaCl concentration in the eluant controlled the rate of CQ elution from the complexes. The examination of the surfactant elution proved that the elution of CQ was dependent on the residual surfactant content of the zeolite/surfactant complexes. Sodium chloride affected the release of both surfactant and CQ from the complexes. Springer-Verlag Berlin Heidelberg, 2000 Key words Adsolubilization nationallicence Drug carrier nationallicence Zeolite nationallicence Cationic surfactant nationallicence Chloroquin nationallicence Hayakawa K. Department of Chemistry and BioScience Faculty of Science Kagoshima University 1-21-35 Korimoto, Kagoshima 890-0065 Japan e-mail: hayak@sci.kagoshima-u.ac.jp Tel.: +81-99-2858101 Fax: +81-99-2858117, JP aut Mouri Y. Department of Chemistry and BioScience Faculty of Science Kagoshima University 1-21-35 Korimoto, Kagoshima 890-0065 Japan e-mail: hayak@sci.kagoshima-u.ac.jp Tel.: +81-99-2858101 Fax: +81-99-2858117, JP aut Maeda T. Department of Chemistry and BioScience Faculty of Science Kagoshima University 1-21-35 Korimoto, Kagoshima 890-0065 Japan e-mail: hayak@sci.kagoshima-u.ac.jp Tel.: +81-99-2858101 Fax: +81-99-2858117, JP aut Satake I. Department of Chemistry and BioScience Faculty of Science Kagoshima University 1-21-35 Korimoto, Kagoshima 890-0065 Japan e-mail: hayak@sci.kagoshima-u.ac.jp Tel.: +81-99-2858101 Fax: +81-99-2858117, JP aut Sato M. Department of Home Economics Faculty of Education Kagoshima University 1-20-6 Korimoto Kagoshima 890-0065, Japan, JP aut https://doi.org/10.1007/s003960050554 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s003960050554 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hayakawa K. Department of Chemistry and BioScience Faculty of Science Kagoshima University 1-21-35 Korimoto, Kagoshima 890-0065 Japan e-mail: hayak@sci.kagoshima-u.ac.jp Tel.: +81-99-2858101 Fax: +81-99-2858117, JP aut NATIONALLICENCE 700 1- Mouri Y. Department of Chemistry and BioScience Faculty of Science Kagoshima University 1-21-35 Korimoto, Kagoshima 890-0065 Japan e-mail: hayak@sci.kagoshima-u.ac.jp Tel.: +81-99-2858101 Fax: +81-99-2858117, JP aut NATIONALLICENCE 700 1- Maeda T. Department of Chemistry and BioScience Faculty of Science Kagoshima University 1-21-35 Korimoto, Kagoshima 890-0065 Japan e-mail: hayak@sci.kagoshima-u.ac.jp Tel.: +81-99-2858101 Fax: +81-99-2858117, JP aut NATIONALLICENCE 700 1- Satake I. Department of Chemistry and BioScience Faculty of Science Kagoshima University 1-21-35 Korimoto, Kagoshima 890-0065 Japan e-mail: hayak@sci.kagoshima-u.ac.jp Tel.: +81-99-2858101 Fax: +81-99-2858117, JP aut NATIONALLICENCE 700 1- Sato M. Department of Home Economics Faculty of Education Kagoshima University 1-20-6 Korimoto Kagoshima 890-0065, Japan, JP aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer