caa a22 4500 475764188 CHVBK 20180406123600.0 cr unu---uuuuu 170329e20000301xx s 000 0 eng 10.1007/s003960050041 doi (NATIONALLICENCE)springer-10.1007/s003960050041 Different methods for the fractionation of magnetic fluids [Elektronische Daten] [T. Rheinländer, R. Kötitz, W. Weitschies, W. Semmler]  Magnetic fluids are used in many fields of application, such as material separation and biomedicine. Magnetic fluids consist of magnetic nanoparticles, which commonly display a broad distribution of magnetic and nonmagnetic parameters. Therefore, upon application only a small number of particles contribute to the desired magnetic effect. In order to optimize magnetic fluids for applications preference is given to methods that separate magnetic nanoparticles according to their magnetic properties. Hence, a magnetic method was developed for the fractionation of magnetic fluids. Familiar size-exclusion chromatography of two different magnetic fluids was carried out for comparison. The fractions obtained and the original samples were also magnetically characterized by magnetic resonance and magnetorelaxometry, two biomedical applications. The size-exclusion fractions are similar to those of magnetic fractionation, despite the different separation mechanisms. In this respect, magnetic fractionation has several advantages in practical use over size-exclusion chromatography: the magnetic method is faster and has a higher capacity. The fractions obtained by both methods show distinctly different magnetic properties compared to the original samples and are therefore especially suited for applications such as magnetorelaxometry. Springer-Verlag Berlin Heidelberg, 2000 Key words Magnetic fluids nationallicence Magnetic nanoparticles nationallicence Magnetic fractionation nationallicence Size-exclusion chromatography nationallicence Magnetic relaxation nationallicence Rheinländer T. Institut für Diagnostikforschung GmbH an der Freien Universität Berlin Spandauer Damm 130 D-14050 Berlin, Germany e-mail: thomas.rheinlaender@charite.de Tel.: +49-30-30390421 Fax: +49-30-30390498, DE aut Kötitz R. Institut für Diagnostikforschung GmbH an der Freien Universität Berlin Spandauer Damm 130 D-14050 Berlin, Germany e-mail: thomas.rheinlaender@charite.de Tel.: +49-30-30390421 Fax: +49-30-30390498, DE aut Weitschies W. Ernst-Moritz-Arndt-Universität Greifswald Institut für Pharmazie Friedrich-Ludwig-Jahn-Strasse 17 D-17487 Greifswald, Germany, DE aut Semmler W. Institut für Diagnostikforschung GmbH an der Freien Universität Berlin Spandauer Damm 130 D-14050 Berlin, Germany e-mail: thomas.rheinlaender@charite.de Tel.: +49-30-30390421 Fax: +49-30-30390498, DE aut https://doi.org/10.1007/s003960050041 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s003960050041 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Rheinländer T. Institut für Diagnostikforschung GmbH an der Freien Universität Berlin Spandauer Damm 130 D-14050 Berlin, Germany e-mail: thomas.rheinlaender@charite.de Tel.: +49-30-30390421 Fax: +49-30-30390498, DE aut NATIONALLICENCE 700 1- Kötitz R. Institut für Diagnostikforschung GmbH an der Freien Universität Berlin Spandauer Damm 130 D-14050 Berlin, Germany e-mail: thomas.rheinlaender@charite.de Tel.: +49-30-30390421 Fax: +49-30-30390498, DE aut NATIONALLICENCE 700 1- Weitschies W. Ernst-Moritz-Arndt-Universität Greifswald Institut für Pharmazie Friedrich-Ludwig-Jahn-Strasse 17 D-17487 Greifswald, Germany, DE aut NATIONALLICENCE 700 1- Semmler W. Institut für Diagnostikforschung GmbH an der Freien Universität Berlin Spandauer Damm 130 D-14050 Berlin, Germany e-mail: thomas.rheinlaender@charite.de Tel.: +49-30-30390421 Fax: +49-30-30390498, DE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer