caa a22 4500 475764854 CHVBK 20180406123602.0 cr unu---uuuuu 170329e20000201xx s 000 0 eng 10.1007/s003960050022 doi (NATIONALLICENCE)springer-10.1007/s003960050022 Dörfler H. -D Technische Universität Dresden, Institut für Physikalische Chemie und Elektrochemie, D-01069 Dresden, Germany, DE aut Relationships between miscibility behavior and chemical structure of phospholipids in pseudobinary systems [Elektronische Daten] [H. -D. Dörfler] The influence of chain length differences of cephalines and the influence of the head group methylation on the miscibility behavior of N-methylated phosphatidylethanolamine (PE) mixtures in aqueous dispersions were tested. Nine different phase diagrams were studied by means of differential scanning calorimetry. The phase diagrams of the five pseudobinary cephaline/cephaline/water systems (fatty acid chain length: C n , n = 12-18) showed that in the high temperature Lα phase all the homologous cephalines were completely miscible. In the low-temperature phase a distinct succession of the phase diagram types was observed according to increasing chain length differences of the PEs: complete miscibilty (C12/C14; C14/C16), peritectic mixing behavior (C12/C16; C14/C18), eutectic mixing behavior (C12/C18). Furthermore four phase diagrams of pseudobinary phospholipid systems consisting of N-methylated PEs with different numbers of methyl groups and a constant length of fatty acid chains were investigated and compared. These four phase diagrams showed phase separations in the low-temperatures phase (gel phase). The width and the concentration range of the miscibility gaps changed systematically with increasing degree of methylation of the head group of the mixing components and are connected with different possibilities of PEs to form hydrogen bridges between the mixture components. Springer-Verlag Berlin Heidelberg, 2000 Key words Phase diagrams nationallicence Pseudobinary systems nationallicence Miscibility nationallicence Calorimetry nationallicence Phospholipids nationallicence https://doi.org/10.1007/s003960050022 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s003960050022 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Dörfler H. -D Technische Universität Dresden, Institut für Physikalische Chemie und Elektrochemie, D-01069 Dresden, Germany, DE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer