caa a22 4500 475766865 CHVBK 20180406123608.0 cr unu---uuuuu 170329e20000401xx s 000 0 eng 10.1007/s007050050669 doi (NATIONALLICENCE)springer-10.1007/s007050050669 Isolation of an attenuated myxoma virus field strain that can confer protection against myxomatosis on contacts of vaccinates [Elektronische Daten] [J. Bárcena, A. Pagès-Manté, R. March, M. Morales, M. A. Ramírez, J. M. Sánchez-Vizcaíno, J. M. Torres] Summary.:  Twenty MV strains obtained from a survey of field strains currently circulating throughout Spain were analyzed for their virulence and horizontal spreading among rabbits by contact transmission. A virus strain with suitable characteristics to be used as a potential vaccine against myxomatosis in wild rabbit populations was selected. Following inoculation, the selected MV strain elicited high levels of MV specificantibodies and induced protection of rabbits against a virulent MV challenge. Furthermore, the attenuated MV was transmitted to 9 out of 16 uninoculated rabbits by contact, inducing protection against myxomatosis. 2000 Springer-Verlag/, Wien Bárcena J. Centro de Investigación en Sanidad Animal (CISA-INIA), Valdeolmos, Madrid, Spain, ES aut Pagès-Manté A. Laboratorios Hipra, S.A., Amer, Girona, Spain, ES aut March R. Laboratorios Hipra, S.A., Amer, Girona, Spain, ES aut Morales M. Centro de Investigación en Sanidad Animal (CISA-INIA), Valdeolmos, Madrid, Spain, ES aut Ramírez M. A. Centro de Investigación en Sanidad Animal (CISA-INIA), Valdeolmos, Madrid, Spain, ES aut Sánchez-Vizcaíno J. M. Centro de Investigación en Sanidad Animal (CISA-INIA), Valdeolmos, Madrid, Spain, ES aut Torres J. M. Centro de Investigación en Sanidad Animal (CISA-INIA), Valdeolmos, Madrid, Spain, ES aut https://doi.org/10.1007/s007050050669 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s007050050669 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bárcena J. Centro de Investigación en Sanidad Animal (CISA-INIA), Valdeolmos, Madrid, Spain, ES aut NATIONALLICENCE 700 1- Pagès-Manté A. Laboratorios Hipra, S.A., Amer, Girona, Spain, ES aut NATIONALLICENCE 700 1- March R. Laboratorios Hipra, S.A., Amer, Girona, Spain, ES aut NATIONALLICENCE 700 1- Morales M. Centro de Investigación en Sanidad Animal (CISA-INIA), Valdeolmos, Madrid, Spain, ES aut NATIONALLICENCE 700 1- Ramírez M. A. Centro de Investigación en Sanidad Animal (CISA-INIA), Valdeolmos, Madrid, Spain, ES aut NATIONALLICENCE 700 1- Sánchez-Vizcaíno J. M. Centro de Investigación en Sanidad Animal (CISA-INIA), Valdeolmos, Madrid, Spain, ES aut NATIONALLICENCE 700 1- Torres J. M. Centro de Investigación en Sanidad Animal (CISA-INIA), Valdeolmos, Madrid, Spain, ES aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer