caa a22 4500 475768124 CHVBK 20180406123612.0 cr unu---uuuuu 170329e20000901xx s 000 0 eng 10.1007/s004270000091 doi (NATIONALLICENCE)springer-10.1007/s004270000091 Hox genes in the honey bee Apis mellifera [Elektronische Daten] [U. Walldorf, P. Binner, R. Fleig] Abstract : Hox genes are known to control the identity of serially repeated structures in arthropods and vertebrates. We analyzed the expression pattern of the Hox genes Deformed (Dfd), Sex combs reduced (Scr), Antennapedia (Antp), and Ultrabithorax/abdominal-A (Ubx/abd-A) from the honey bee Apis mellifera. We also cloned a cDNA with the complete coding region of the Antennapedia gene from Apis. Comparison with Antp proteins from other insect species revealed several regions of homology. The expression patterns of the isolated Hox genes from Apis showed that the original expression patterns of Dfd, Scr, and Antp appear between late blastoderm and early germ band stage in a temporal and spatial sequence. Each of them shows up as a belt, spanning approximately two segment anlagen, Dfd in the anterior gnathal region, Scr in the posterior gnathal and anterior thoracic region, and Antp in the thoracic region. Following expansion of the Antp domain in the abdomen as a gradient towards the posterior, Ubx/abd-A expression appears laterally in the abdomen. During gastrulation and in the germ band stage the domains of strong expression do not overlap any more, but touch each other. After gastrulation the borders of the expression domains partly correlate with parasegment and partly with segment boundaries. Laterally, gaps between the domain of each gene may show no expression of any of the genes examined. Springer-Verlag Berlin Heidelberg, 2000 Key words  Dfd nationallicence Scr nationallicence Antp nationallicence Ubx nationallicence abd-A nationallicence Walldorf U. Institut für Genetik, Universität Hohenheim, Garbenstrasse 30, 70593 Stuttgart, Germany e-mail: walldorf@uni-hohenheim.de Tel.: +49-711-4592208, Fax: +49-711-4592211, DE aut Binner P. Institut für Biologie I (Zoologie), Universität Freiburg, Hauptstrasse 1, 79104 Freiburg, Germany, DE aut Fleig R. Institut für Zoologie, Technische Universität Dresden, Mommsenstrasse 13, 01062 Dresden, Germany, DE aut https://doi.org/10.1007/s004270000091 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004270000091 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Walldorf U. Institut für Genetik, Universität Hohenheim, Garbenstrasse 30, 70593 Stuttgart, Germany e-mail: walldorf@uni-hohenheim.de Tel.: +49-711-4592208, Fax: +49-711-4592211, DE aut NATIONALLICENCE 700 1- Binner P. Institut für Biologie I (Zoologie), Universität Freiburg, Hauptstrasse 1, 79104 Freiburg, Germany, DE aut NATIONALLICENCE 700 1- Fleig R. Institut für Zoologie, Technische Universität Dresden, Mommsenstrasse 13, 01062 Dresden, Germany, DE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer