caa a22 4500 475768418 CHVBK 20180406123613.0 cr unu---uuuuu 170329e20001001xx s 000 0 eng 10.1007/s004270000096 doi (NATIONALLICENCE)springer-10.1007/s004270000096 X-linked loci of Drosophila melanogaster causing defects in the morphology of the embryonic salivary glands [Elektronische Daten] [U. Lammel, H. Saumweber] Abstract : To identify X chromosomal genes required for salivary gland development in the Drosophila embryo, we screened embryos hemizygous for EMS-induced lethal mutations to find mutations causing gross morphological defects in salivary gland development. The parental strain carried a lac Z transgene on the second chromosome, which was specifically expressed in the salivary glands so the mutations could be unambiguously identified. Embryos from 3,383 lines were tested for salivary gland abnormalities following lacZ staining. From 63 lines exhibiting aberrant salivary gland phenotypes, 52 stable lines were established containing mutations affecting salivary gland development. From these, 39 lines could be assigned to nine complementation groups: armadillo, brinker, folded gastrulation, giant, hindsight, Notch, runt, stardust and twisted gastrulation. Springer-Verlag Berlin Heidelberg, 2000 Key words Organogenesis nationallicence Embryonic lethal mutations nationallicence Enhancer trap nationallicence LacZ staining nationallicence Lammel U. Humboldt-Universitaet zu Berlin, Institut fuer Biologie Abteilung Zytogenetik, Chausseestrasse 117, 10115 Berlin, Germany e-mail: saumweber@biologie.hu-berlin.de Tel.: +49-30-20938178, Fax: +49-30-20938177, DE aut Saumweber H. Humboldt-Universitaet zu Berlin, Institut fuer Biologie Abteilung Zytogenetik, Chausseestrasse 117, 10115 Berlin, Germany e-mail: saumweber@biologie.hu-berlin.de Tel.: +49-30-20938178, Fax: +49-30-20938177, DE aut https://doi.org/10.1007/s004270000096 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004270000096 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lammel U. Humboldt-Universitaet zu Berlin, Institut fuer Biologie Abteilung Zytogenetik, Chausseestrasse 117, 10115 Berlin, Germany e-mail: saumweber@biologie.hu-berlin.de Tel.: +49-30-20938178, Fax: +49-30-20938177, DE aut NATIONALLICENCE 700 1- Saumweber H. Humboldt-Universitaet zu Berlin, Institut fuer Biologie Abteilung Zytogenetik, Chausseestrasse 117, 10115 Berlin, Germany e-mail: saumweber@biologie.hu-berlin.de Tel.: +49-30-20938178, Fax: +49-30-20938177, DE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer