caa a22 4500 475771265 CHVBK 20180406123617.0 cr unu---uuuuu 170329e20000601xx s 000 0 eng 10.1007/s001250051366 doi (NATIONALLICENCE)springer-10.1007/s001250051366 Triglycerides, apo C3 and Lp B:C3 and cardiovascular risk in Type II diabetes [Elektronische Daten] [N. Gervaise, M. A. Garrigue, G. Lasfargues, P. Lecomte] Aims/hypothesis. Cardiovascular complications and particularly coronary heart disease are the main causes of morbidity and mortality in Type II (non-insulin-dependent) diabetes mellitus. Some studies have shown that hypertriglyceridaemia in diabetes is an independent cardiovascular risk factor. In the ECTIM study high apolipoprotein C3 and lipoprotein B:C3 concentrations (lipoparticles playing a role in triglyceride metabolism) were associated with myocardial infarction in non-diabetic subjects.¶Methods. We studied the relations between macroangiopathy and different cardiovascular risk factors and lipid variables in 188 Type II diabetic subjects.¶Results. Multivariate analysis showed that triglycerides, apo C3 and Lp B:C3, sex, duration of diabetes, microalbuminuria and age were independently associated with macroangiopathy. The study group was divided into quartiles according to apo C3 and Lp B:C3 concentrations: the prevalence of macroangiopathy and coronary heart disease were increased in upper quartiles.¶Conclusion/interpretation. Triglycerides apo C3 and Lp B:C3 were independent cardiovascular risk markers in our group of Type II diabetic patients. [Diabetologia (2000) 43: 703-708] Springer-Verlag Berlin Heidelberg, 2000 Keywords Type II diabetes, triglycerides, apolipoprotein C3, lipoprotein B:C3, cardiovascular risk, macroangiopathy, CHD nationallicence Gervaise N. Endocrine Unit, CHU Bretonneau, Tours, France, FR aut Garrigue M. A. Biochemistry Laboratory, CHU Bretonneau, Tours, France, FR aut Lasfargues G. Endocrine Unit, CHU Bretonneau, Tours, France, FR aut Lecomte P. Endocrine Unit, CHU Bretonneau, Tours, France, FR aut https://doi.org/10.1007/s001250051366 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s001250051366 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gervaise N. Endocrine Unit, CHU Bretonneau, Tours, France, FR aut NATIONALLICENCE 700 1- Garrigue M. A. Biochemistry Laboratory, CHU Bretonneau, Tours, France, FR aut NATIONALLICENCE 700 1- Lasfargues G. Endocrine Unit, CHU Bretonneau, Tours, France, FR aut NATIONALLICENCE 700 1- Lecomte P. Endocrine Unit, CHU Bretonneau, Tours, France, FR aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer