caa a22 4500 475773470 CHVBK 20180406123624.0 cr unu---uuuuu 170329e20000301xx s 000 0 eng 10.1023/A:1007108201320 doi (NATIONALLICENCE)springer-10.1023/A:1007108201320 Alpha adrenergic blockers in the treatment of benign hyperplasia of the prostate [Elektronische Daten] [V.L. Kumar, S. Dewan] Benign prostatic hyperplasia (BPH), a common benign tumor in men has been attributed to age and male androgen functions. Of the various management options for treatment of BPH, medical therapy is the first line treatment modality involving either blockade of alpha adrenergic receptors or inhibition of 5-alpha reductase. Amongst these, the alpha-1 blockers are used most frequently. The association of numerous adverse effects with non selective and short acting alpha-1 blockers (like phenoxybenzamine, prazosin and alfuzosin) has led to the development of long acting alpha-1 adrenoceptor blockers (doxazosin, terazosin, tamulosin) which being uroselective significantly reduce the incidence of cardiovascular side effects and increase patient compliance. The review gives a brief account of pharmacological properties and efficacy of alpha adrenergic receptor blockers in the treatment of BPH. Kluwer Academic Publishers, 2000 Benign tumor nationallicence Alpha blockers nationallicence Prostate nationallicence Kumar V.L. Department of Pharmacology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India aut Dewan S. Department of Pharmacology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India aut International Urology and Nephrology Kluwer Academic Publishers 32/1(2000-03-01), 67-71 0301-1623 32:1<67 2000 32 11255 https://doi.org/10.1023/A:1007108201320 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1007108201320 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kumar V.L. Department of Pharmacology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India aut NATIONALLICENCE 700 1- Dewan S. Department of Pharmacology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India aut NATIONALLICENCE 773 0- International Urology and Nephrology Kluwer Academic Publishers 32/1(2000-03-01), 67-71 0301-1623 32:1<67 2000 32 11255 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer