caa a22 4500 475773888 CHVBK 20180406123625.0 cr unu---uuuuu 170329e20000601xx s 000 0 eng 10.1023/A:1007135517950 doi (NATIONALLICENCE)springer-10.1023/A:1007135517950 Hyperkalemia in hospitalized patients [Elektronische Daten] [Robert Dunlay, Marc Stevens] Objective: Evaluate the prevalence of hyperkalemia(potassium < 5.5 mmol/l) in hospitalized patientsnot on dialysis, as well as the association ofmedications, impaired renal function and comorbidconditions with hyperkalemia.Design: A retrospective case-control method.Setting: A tertiary care teaching hospital.Patients: Hyperkalemic adults not on dialysis withage and sex matched controls.Interventions: None.Main outcome measures: The use of medicationsassociated with hyperkalemia and renal function usinga calculated creatinine clearance were compared in thehyperkalemic and control groups.Results: 35 adult patients with hyperkalemia who werenot receiving dialysis were identified, with aprevalence in the hospitalized population of 3.3%.The hyperkalemic patients were older than the generalhospital population (p < 0.05). Compared withcontrols, hyperkalemic patients: had a lowercreatinine clearance (p < 0.05), were more likely tobe taking angiotensin-converting enzyme inhibitors (p < 0.05), and had an increased frequency of diabetesmellitus (p < 0.001). All of the control patientssurvived their hospitalization, but the mortality rate in the hyperkalemic group was 17% (p < 0.0001). Noneof the deaths were directly attributable to hyperkalemia.Conclusions: Hyperkalemia is more frequent in olderpatients and is usually mild. Hyperkalemia isassociated with diabetes mellitus, diminished renalfunction and the use of angiotensin-converting enzymeinhibitors. An elevated serum potassium level in ahospitalized patient may be a marker for asignificantly increased risk of death, which is due tounderlying medical problems and is not a consequenceof the hyperkalemia. Kluwer Academic Publishers, 2000 Angiotensin-converting enzyme inhibitors nationallicence Hyperkalemia nationallicence Potassium nationallicence Dunlay Robert Departments of Medicine and Pharmacology, Creighton University, Omaha, Nebraska, USA aut Stevens Marc Departments of Medicine and Pharmacology, Creighton University, Omaha, Nebraska, USA aut International Urology and Nephrology Kluwer Academic Publishers 32/2(2000-06-01), 177-180 0301-1623 32:2<177 2000 32 11255 https://doi.org/10.1023/A:1007135517950 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1007135517950 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dunlay Robert Departments of Medicine and Pharmacology, Creighton University, Omaha, Nebraska, USA aut NATIONALLICENCE 700 1- Stevens Marc Departments of Medicine and Pharmacology, Creighton University, Omaha, Nebraska, USA aut NATIONALLICENCE 773 0- International Urology and Nephrology Kluwer Academic Publishers 32/2(2000-06-01), 177-180 0301-1623 32:2<177 2000 32 11255 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer