caa a22 4500 475775023 CHVBK 20180406123629.0 cr unu---uuuuu 170329e20000201xx s 000 0 eng 10.1007/s004180050012 doi (NATIONALLICENCE)springer-10.1007/s004180050012 Concomitant increases in myonuclear and satellite cell content in female trapezius muscle following strength training [Elektronische Daten] [F. Kadi, Lars-Eric Thornell] Abstract : A skeletal muscle fibre maintains its cytoplasmic volume by means of hundreds of myonuclei distributed along its entire length. Therefore it is hypothesised that changes in fibre size would involve modifications in myonuclear number. In this study, we have examined whether 10 weeks of strength training can induce changes in the number of myonuclei and satellite cells in female trapezius muscles. Biopsies were taken pre- and posttraining from the upper part of the descending trapezius muscle of nine subjects. Muscle samples were analysed for fibre area and myonuclear and satellite cell number using immunohistochemistry. There was a 36% increase in the cross-sectional area of muscle fibres. The hypertrophy of muscle fibres was accompanied by an approximately 70% increase in myonuclear number and a 46% increase in the number of satellite cells. Myonuclei number was positively correlated to satellite cell number indicating that a muscle with an increased concentration of myonuclei will contain a correspondingly higher number of satellite cells. The acquisition of additional myonuclei appears to be required to support the enlargement of multinucleated muscle cells following 10 weeks of strength training. Increased satellite cell content suggests that mitotic divisions of satellite cells produced daughter cells that became satellite cells. Springer-Verlag Berlin Heidelberg, 2000 Kadi F. Department of Integrative Medical Biology, Section for Anatomy, Umeå University, 901 87, Umeå, Sweden e-mail: fawzi.kadi@anatomy.umu.se Tel.: +46-90-7865122, Fax: +46-90-7865480, SE aut Thornell Lars-Eric Department of Integrative Medical Biology, Section for Anatomy, Umeå University, 901 87, Umeå, Sweden e-mail: fawzi.kadi@anatomy.umu.se Tel.: +46-90-7865122, Fax: +46-90-7865480, SE aut https://doi.org/10.1007/s004180050012 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004180050012 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kadi F. Department of Integrative Medical Biology, Section for Anatomy, Umeå University, 901 87, Umeå, Sweden e-mail: fawzi.kadi@anatomy.umu.se Tel.: +46-90-7865122, Fax: +46-90-7865480, SE aut NATIONALLICENCE 700 1- Thornell Lars-Eric Department of Integrative Medical Biology, Section for Anatomy, Umeå University, 901 87, Umeå, Sweden e-mail: fawzi.kadi@anatomy.umu.se Tel.: +46-90-7865122, Fax: +46-90-7865480, SE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer