caa a22 4500 475778766 CHVBK 20180406123638.0 cr unu---uuuuu 170329e20000101xx s 000 0 eng 10.1007/s004649900009 doi (NATIONALLICENCE)springer-10.1007/s004649900009 Endosonographic examination of gastrointestinal anastomoses with suspected locoregional tumor recurrence [Elektronische Daten] [C. Müller, G. Kähler, J. Scheele] Background: Endoscopic ultrasound is considered one of the best tools for the preoperative staging of esophageal, gastric, and rectal carcinoma. Depending on the individual investigator, the sensitivity of preoperative tumor staging by endosonography of the upper gastrointestinal tract (GEUS) is 80-92% for gastric carcinoma and 86-95% for esophageal carcinoma. However, the sensitivity and specificity of endosonography for the staging of lymph node metastases is less accurate. The accuracy of rectal endosonography (REUS) is ≈90% for tumor assessment and ≈80% for the detection of lymph node metastases. In this study, we address the question of whether endosonography enables the surgeon to distinguish scar tissue, which is rather homogeneous and echo-rich, from changes such as an anastomositis or a locoregional tumor recurrence, which are typically non-inhomogeneous and echo-poor. Methods: During a 24-months period, we studied patients enrolled in a special tumor follow-up care program by either upper gastrointestinal (GEUS, n=37 patients) or rectal endosonography (REUS, n=49 patients) for exclusion of a locoregional tumor recurrence. In each patient, local tumor recurrence was suspected because of either medical history, clinical examination, or other diagnostic procedures. Results: As in previous studies, our retrospective analysis revealed that endosonography has a high sensitivity in the detection of local tumor recurrences (>90%) for both GEUS and REUS. Conclusion: Endosonography is a highly accurate means of detecting local tumor recurrence. Springer-Verlag, 2000 Endosonography nationallicence Gastrointestinal tract carcinoma nationallicence Locoregional tumor recurrence nationallicence Anastomosis nationallicence Cancer nationallicence Müller C. Department of General and Visceral Surgery, Friedrich Schiller University of Jena, D-07740, Jena, Germany aut Kähler G. Department of General and Visceral Surgery, Friedrich Schiller University of Jena, D-07740, Jena, Germany aut Scheele J. Department of General and Visceral Surgery, Friedrich Schiller University of Jena, D-07740, Jena, Germany aut Surgical Endoscopy Springer-Verlag 14/1(2000-01-01), 45-50 0930-2794 14:1<45 2000 14 464 https://doi.org/10.1007/s004649900009 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004649900009 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Müller C. Department of General and Visceral Surgery, Friedrich Schiller University of Jena, D-07740, Jena, Germany aut NATIONALLICENCE 700 1- Kähler G. Department of General and Visceral Surgery, Friedrich Schiller University of Jena, D-07740, Jena, Germany aut NATIONALLICENCE 700 1- Scheele J. Department of General and Visceral Surgery, Friedrich Schiller University of Jena, D-07740, Jena, Germany aut NATIONALLICENCE 773 0- Surgical Endoscopy Springer-Verlag 14/1(2000-01-01), 45-50 0930-2794 14:1<45 2000 14 464 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer