caa a22 4500 475780272 CHVBK 20180406123642.0 cr unu---uuuuu 170329e20001001xx s 000 0 eng 10.1007/s004640000180 doi (NATIONALLICENCE)springer-10.1007/s004640000180 Peritoneal adhesions to prosthetic materials [Elektronische Daten] Choice of mesh for incisional hernia repair [W. Vrijland, F. Bonthuis, E. Steyerberg, R. Marquet, J. Jeekel, H. Bonjer] Background: In many cases, incisional hernia repair requires the use of prosthetic materials. The aim of this experimental study in a rat model was to assess the role of polyglactin 910 mesh and fluoropassivated polyester mesh in preventing the formation of adhesions. Methods: In the first experiment, the formation of peritoneal adhesions was assessed after insertion of polypropylene, polypropylene combined with polyglactin 910, or no mesh. In the second experiment, adhesion formations were compared after insertion of fluoropassivated polyester, polypropylene, and no mesh. Results: The first experiment showed no significant difference in adhesion formations between the polypropylene mesh and the combined mesh; however, when no mesh was used, there were significantly fewer adhesions in both experiments (p<0.01). The second experiment showed a significantly lower degree of adhesions and a lower Adhesion Index after insertion of fluoropassivated polyester mesh than when polypropylene mesh was used (p=0.04). Conclusions: Adding polyglactin 910 mesh to polypropylene mesh to prevent the formation of adhesions is not an effective measure. Fluoropassivated polyester meshes appear to provide a better alternative to the use of polypropylene meshes for incisional hernia repair in humans in terms of the formation of adhesions. Springer-Verlag, 2000 Adhesions nationallicence Prosthetic materials nationallicence Mesh nationallicence Rat nationallicence Incisional hernia nationallicence Hernia repair nationallicence Vrijland W. Department of General Surgery, Erasmus University Medical Center, P. O. Box 2040, 300 CA, Rotterdam, The Netherlands aut Bonthuis F. Laboratory for Experimental Surgery, Erasmus University Medical Center, P. O. Box 2040, 3000 CA, Rotterdam, The Netherlands aut Steyerberg E. Department of Public Health, Erasmus University Medical Center, P. O. Box 2040, 3000 CA, Rotterdam, The Netherlands aut Marquet R. Department of General Surgery, Erasmus University Medical Center, P. O. Box 2040, 300 CA, Rotterdam, The Netherlands aut Jeekel J. Department of General Surgery, Erasmus University Medical Center, P. O. Box 2040, 300 CA, Rotterdam, The Netherlands aut Bonjer H. Department of General Surgery, Erasmus University Medical Center, P. O. Box 2040, 300 CA, Rotterdam, The Netherlands aut Surgical Endoscopy Springer-Verlag 14/10(2000-10-01), 960-963 0930-2794 14:10<960 2000 14 464 https://doi.org/10.1007/s004640000180 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004640000180 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Vrijland W. Department of General Surgery, Erasmus University Medical Center, P. O. Box 2040, 300 CA, Rotterdam, The Netherlands aut NATIONALLICENCE 700 1- Bonthuis F. Laboratory for Experimental Surgery, Erasmus University Medical Center, P. O. Box 2040, 3000 CA, Rotterdam, The Netherlands aut NATIONALLICENCE 700 1- Steyerberg E. Department of Public Health, Erasmus University Medical Center, P. O. Box 2040, 3000 CA, Rotterdam, The Netherlands aut NATIONALLICENCE 700 1- Marquet R. Department of General Surgery, Erasmus University Medical Center, P. O. Box 2040, 300 CA, Rotterdam, The Netherlands aut NATIONALLICENCE 700 1- Jeekel J. Department of General Surgery, Erasmus University Medical Center, P. O. Box 2040, 300 CA, Rotterdam, The Netherlands aut NATIONALLICENCE 700 1- Bonjer H. Department of General Surgery, Erasmus University Medical Center, P. O. Box 2040, 300 CA, Rotterdam, The Netherlands aut NATIONALLICENCE 773 0- Surgical Endoscopy Springer-Verlag 14/10(2000-10-01), 960-963 0930-2794 14:10<960 2000 14 464 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer