caa a22 4500 475781570 CHVBK 20180406123646.0 cr unu---uuuuu 170329e20000201xx s 000 0 eng 10.1007/s004649900080 doi (NATIONALLICENCE)springer-10.1007/s004649900080 Transesophageal echocardiographic assessment of hemodynamic function during laparoscopic cholecystectomy in healthy patients [Elektronische Daten] [D. D'Ugo, R. Persiani, F. Pennestri, E. Adducci, P. Primieri, V. Pende, G. De Cosmo] Background: This study aimed by means of transesophageal echocardiography, to evaluate hemodynamic changes induced by pneumoperitoneum in patients with normal cardiac performance. Methods: In this study, 11 ASA I-II patients (mean age, 39 years) with normal cardiac performance undergoing laparoscopic cholecystectomy were evaluated. A 5-MHz transesophageal biplane phased-array transducer connected to an echocardiographer was inserted after induction of anesthesia. Data were collected at three different times: before insufflation (T1), 10 min after insufflation (T2), and 5 min after desufflation (T3). At these same times, heart rate, systolic blood pressure, diastolic blood pressure, end-tidal carbon dioxide (CO2), and peak airway pressure were recorded. Statistical analysis was performed using one-way and two-way analysis of variance (ANOVA). A p value less than 0.05 was considered significant. Results: End-systolic and end-diastolic diameters of the left ventricle, contractility, and performance parameters did not change significantly. Conversely, at insufflation, color Doppler area of the mitral backflow increased significantly (p < 0.05) when already present or showed up abruptly (T1: 0.22 ± 0.28 cm2; T2: 1.28 ± 1.02 cm2; T3: 0.49 ± 0.53 cm2). Conclusions: Such an event is not interpreted as a mitral insufficiency. It is possibly the result of a 's'scontrast effect'' caused by the absorption of CO2 microbubbles in the blood. Springer-Verlag New York Inc., 2000 Key words: Hemodynamic changes — Laparoscopic cholecystectomy — Transesophageal echocardiography nationallicence D'Ugo D. Department of Surgery, Catholic University of Rome, "A Gemelli” Medical School, Largo F. Vito 1, 00168 Rome, Italy, Italy aut Persiani R. Department of Surgery, Catholic University of Rome, "A Gemelli” Medical School, Largo F. Vito 1, 00168 Rome, Italy, Italy aut Pennestri F. Department of Cardiology, Catholic University of Rome, "A Gemelli” Medical School, Largo F. Vito 1, 00168 Rome, Italy, Italy aut Adducci E. Department of Anaesthesiology, Catholic University of Rome, "A Gemelli” Medical School, Largo F. Vito 1, 00168 Rome, Italy, Italy aut Primieri P. Department of Anaesthesiology, Catholic University of Rome, "A Gemelli” Medical School, Largo F. Vito 1, 00168 Rome, Italy, Italy aut Pende V. Department of Surgery, Catholic University of Rome, "A Gemelli” Medical School, Largo F. Vito 1, 00168 Rome, Italy, Italy aut De Cosmo G. Department of Anaesthesiology, Catholic University of Rome, "A Gemelli” Medical School, Largo F. Vito 1, 00168 Rome, Italy, Italy aut Surgical Endoscopy Springer-Verlag 14/2(2000-02-01), 120-122 0930-2794 14:2<120 2000 14 464 https://doi.org/10.1007/s004649900080 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004649900080 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- D'Ugo D. Department of Surgery, Catholic University of Rome, "A Gemelli” Medical School, Largo F. Vito 1, 00168 Rome, Italy, Italy aut NATIONALLICENCE 700 1- Persiani R. Department of Surgery, Catholic University of Rome, "A Gemelli” Medical School, Largo F. Vito 1, 00168 Rome, Italy, Italy aut NATIONALLICENCE 700 1- Pennestri F. Department of Cardiology, Catholic University of Rome, "A Gemelli” Medical School, Largo F. Vito 1, 00168 Rome, Italy, Italy aut NATIONALLICENCE 700 1- Adducci E. Department of Anaesthesiology, Catholic University of Rome, "A Gemelli” Medical School, Largo F. Vito 1, 00168 Rome, Italy, Italy aut NATIONALLICENCE 700 1- Primieri P. Department of Anaesthesiology, Catholic University of Rome, "A Gemelli” Medical School, Largo F. Vito 1, 00168 Rome, Italy, Italy aut NATIONALLICENCE 700 1- Pende V. Department of Surgery, Catholic University of Rome, "A Gemelli” Medical School, Largo F. Vito 1, 00168 Rome, Italy, Italy aut NATIONALLICENCE 700 1- De Cosmo G. Department of Anaesthesiology, Catholic University of Rome, "A Gemelli” Medical School, Largo F. Vito 1, 00168 Rome, Italy, Italy aut NATIONALLICENCE 773 0- Surgical Endoscopy Springer-Verlag 14/2(2000-02-01), 120-122 0930-2794 14:2<120 2000 14 464 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer